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The Roles of Phytochemicals in Bronchial Asthma
Department of Internal Medicine, Chungnam National University Medical School, Daejeon, Korea
Department of Internal Medicine, Research Center for Pulmonary Disorders, Chonbuk National University Medical School, San 2-20 Geumam-dong, Deokjin-gu, Jeonju, Jeonbuk 561-180, Korea
* Author to whom correspondence should be addressed.
Received: 9 August 2010; in revised form: 16 September 2010 / Accepted: 30 September 2010 / Published: 4 October 2010
Abstract: Despite gaps in our knowledge of how phytochemicals interfere with cellular functions, several natural plant products are utilized to prevent or treat a wide range of diseases. Identification of an agent with therapeutic potential requires multiple steps involving in vitro studies, efficacy and toxicity studies in animal models, and then human clinical trials. This review provides a brief introduction on natural products that may help to treat and/or prevent bronchial asthma and describes our current understanding of their molecular mechanisms based on various in vitro, in vivo, and clinical studies. We focus on the anti-inflammatory and anti-vascular actions of the plant products and other roles beyond the anti-oxidative effects.
Keywords: antioxidants; bronchial asthma; plant
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Park, H.S.; Kim, S.R.; Kim, J.O.; Lee, Y.C. The Roles of Phytochemicals in Bronchial Asthma. Molecules 2010, 15, 6810-6834.
Park HS, Kim SR, Kim JO, Lee YC. The Roles of Phytochemicals in Bronchial Asthma. Molecules. 2010; 15(10):6810-6834.
Park, Hee Sun; Kim, So Ri; Kim, Ju Ock; Lee, Yong Chul. 2010. "The Roles of Phytochemicals in Bronchial Asthma." Molecules 15, no. 10: 6810-6834.