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Molecules 2009, 14(9), 3676-3687; doi:10.3390/molecules14093676
Article

Synthesis and Antifungal Activity of 5-Chloro-6-Phenylpyridazin-3(2H)-one Derivatives

, * ,
,
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Key Laboratory of Green Pesticide and Agriculture Bioengineering, Ministry of Education, Research and Development Center for Fine Chemicals, Guizhou University, Guiyang 550025, China
* Author to whom correspondence should be addressed.
Received: 27 July 2009 / Revised: 13 September 2009 / Accepted: 16 September 2009 / Published: 18 September 2009
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Abstract

An effective method has been developed for the preparation under mild conditions of novel pyridazine derivatives from the easily accessible starting materials mucochloric acid and benzene. All the synthesized compounds were fully characterized and some of them displayed good antifungal activities against G. zeae, F. oxysporum and C. mandshurica in preliminary antifungal activity tests.
Keywords: pyridazine derivatives; synthesis; antifungal activity pyridazine derivatives; synthesis; antifungal activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Wu, J.; Song, B.; Chen, H.; Bhadury, P.; Hu, D. Synthesis and Antifungal Activity of 5-Chloro-6-Phenylpyridazin-3(2H)-one Derivatives. Molecules 2009, 14, 3676-3687.

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