Molecules 2009, 14(9), 3153-3160; doi:10.3390/molecules14093153
Article

Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media

1,* email, 1, 2 and 3
Received: 19 July 2009; in revised form: 18 August 2009 / Accepted: 25 August 2009 / Published: 26 August 2009
Download PDF [171 KB, uploaded 18 June 2014]
Abstract: A highly efficient palladium acetate-catalyzed ligand-free Suzuki reaction of 2,3,5-trichloropyridine with arylboronic acids in aqueous phase was developed. High yields of 3,5-dichloro-2-arylpyridines, a simple Pd source, absence of ligands, and environmentally benign as well as mild reaction conditions are important features of this method.
Keywords: Suzuki reaction; ligand-free; aqueous phase; 2; 3; 5-trichloropyridine; 3; 5-dichloro-2-arylpyridines
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Hu, H.; Ge, C.; Zhang, A.; Ding, L. Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media. Molecules 2009, 14, 3153-3160.

AMA Style

Hu H, Ge C, Zhang A, Ding L. Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media. Molecules. 2009; 14(9):3153-3160.

Chicago/Turabian Style

Hu, Huanan; Ge, Changhua; Zhang, Anjiang; Ding, Lisheng. 2009. "Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media." Molecules 14, no. 9: 3153-3160.


Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert