Molecules 2009, 14(5), 1818-1824; doi:10.3390/molecules14051818

Phenoxypropylamines: Synthesis and Antiulcer Evaluation

1, 2,* email, 1email, 3email, 4email and 5email
Received: 9 April 2009; Accepted: 8 May 2009 / Published: 13 May 2009
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: We have synthesized a number of phenoxypropylamines from N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}chloroacetamide (3). All the products have been characterized by elemental analysis, 1H-NMR and MS. The biological activity effects of the title compounds were examined. From the biological activity results, we found that two of themshowed significant gastric acid antisecretory activity.
Keywords: roxatidine; synthesis; antiulcer agents; phenoxypropylamine; biological activity
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MDPI and ACS Style

Zhang, H.; Zhang, B.-Y.; Zhang, Q.-Y.; Zhao, D.-M.; Wang, J.-M. Phenoxypropylamines: Synthesis and Antiulcer Evaluation. Molecules 2009, 14, 1818-1824.

AMA Style

Zhang H, Zhang B-Y, Zhang Q-Y, Zhao D-M, Wang J-M. Phenoxypropylamines: Synthesis and Antiulcer Evaluation. Molecules. 2009; 14(5):1818-1824.

Chicago/Turabian Style

Zhang, Hui; Zhang, Bao-Yan; Zhang, Qian-Yun; Zhao, Dong-Mei; Wang, Jia-Mei. 2009. "Phenoxypropylamines: Synthesis and Antiulcer Evaluation." Molecules 14, no. 5: 1818-1824.

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