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Molecules 2009, 14(5), 1818-1824; doi:10.3390/molecules14051818
Article

Phenoxypropylamines: Synthesis and Antiulcer Evaluation

1, 2,* , 1
, 3
, 4
 and 5
Received: 9 April 2009; Accepted: 8 May 2009 / Published: 13 May 2009
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Abstract: We have synthesized a number of phenoxypropylamines from N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}chloroacetamide (3). All the products have been characterized by elemental analysis, 1H-NMR and MS. The biological activity effects of the title compounds were examined. From the biological activity results, we found that two of themshowed significant gastric acid antisecretory activity.
Keywords: roxatidine; synthesis; antiulcer agents; phenoxypropylamine; biological activity roxatidine; synthesis; antiulcer agents; phenoxypropylamine; biological activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Zhang, H.; Zhang, B.-Y.; Zhang, Q.-Y.; Zhao, D.-M.; Wang, J.-M. Phenoxypropylamines: Synthesis and Antiulcer Evaluation. Molecules 2009, 14, 1818-1824.

AMA Style

Zhang H, Zhang B-Y, Zhang Q-Y, Zhao D-M, Wang J-M. Phenoxypropylamines: Synthesis and Antiulcer Evaluation. Molecules. 2009; 14(5):1818-1824.

Chicago/Turabian Style

Zhang, Hui; Zhang, Bao-Yan; Zhang, Qian-Yun; Zhao, Dong-Mei; Wang, Jia-Mei. 2009. "Phenoxypropylamines: Synthesis and Antiulcer Evaluation." Molecules 14, no. 5: 1818-1824.


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