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Synthesis of Hydroxytyrosyl Alkyl Ethers from Olive Oil Waste Waters
Dpto. Química Orgánica y Farmacéutica, Facultad de Farmacia, C/ Prof. García González, 2, Universidad de Sevilla, 41012-Sevilla, Spain
Centro Venta del Llano (IFAPA), 23620-Mengíbar (Jaén), Spain
Instituto de la Grasa (CSIC), Avda. Padre García Tejero, 4, 41012-Sevilla, Spain
* Author to whom correspondence should be addressed.
Received: 24 April 2009; in revised form: 6 May 2009 / Accepted: 8 May 2009 / Published: 11 May 2009
Abstract: The preparation of a new type of derivatives of the naturally occurring antioxidant hydroxytyrosol is reported. Hydroxytyrosyl alkyl ethers were obtained in high yield by a three-step procedure starting from hydroxytyrosol isolated from olive oil waste waters. Preliminary results obtained by the Rancimat method have shown that these derivatives retain the high protective capacity of free hydroxytyrosol.
Keywords: Ethers; hydroxytyrosol; natural products; antioxidants; olive oil; waste waters
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MDPI and ACS Style
Madrona, A.; Pereira-Caro, G.; Mateos, R.; Rodríguez, G.; Trujillo, M.; Fernández-Bolaños, J.; Espartero, J.L. Synthesis of Hydroxytyrosyl Alkyl Ethers from Olive Oil Waste Waters. Molecules 2009, 14, 1762-1772.
Madrona A, Pereira-Caro G, Mateos R, Rodríguez G, Trujillo M, Fernández-Bolaños J, Espartero JL. Synthesis of Hydroxytyrosyl Alkyl Ethers from Olive Oil Waste Waters. Molecules. 2009; 14(5):1762-1772.
Madrona, Andrés; Pereira-Caro, Gema; Mateos, Raquel; Rodríguez, Guillermo; Trujillo, Mariana; Fernández-Bolaños, Juan; Espartero, José L. 2009. "Synthesis of Hydroxytyrosyl Alkyl Ethers from Olive Oil Waste Waters." Molecules 14, no. 5: 1762-1772.