Next Article in Journal
Taiwanese Native Plants Inhibit Matrix Metalloproteinase-9 Activity after Ultraviolet B Irradiation
Previous Article in Journal
Evaluation of Photoluminescence Properties of Some Poly(ethylene glycol) – Supported Coumarin Derivatives
Article Menu

Export Article

Open AccessArticle
Molecules 2009, 14(3), 1056-1061; doi:10.3390/molecules14031056

Efficient One-Pot Synthesis of Indol-3-yl-Glycines via Uncatalyzed Friedel-Crafts Reaction in Water

School of Chemistry, University College of Science, University of Tehran, Tehran, Iran
*
Author to whom correspondence should be addressed.
Received: 11 February 2009 / Revised: 25 February 2009 / Accepted: 3 March 2009 / Published: 5 March 2009
View Full-Text   |   Download PDF [105 KB, uploaded 18 June 2014]   |  

Abstract

The three component reaction of primary aliphatic amines, glyoxalic acid and indole or N-methylindole in water at ambient temperature affords indol-3-yl or N-methylindol-3-yl-glycine in almost quantitative yields. View Full-Text
Keywords: Amino acid; Indol-3-yl-glycine; Glyoxalic acid; Friedel-Crafts reaction Amino acid; Indol-3-yl-glycine; Glyoxalic acid; Friedel-Crafts reaction
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

MDPI and ACS Style

Ghandi, M.; Taheri, A. Efficient One-Pot Synthesis of Indol-3-yl-Glycines via Uncatalyzed Friedel-Crafts Reaction in Water. Molecules 2009, 14, 1056-1061.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top