Molecules 2009, 14(2), 763-770; doi:10.3390/molecules14020763
Article

Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones

Chen-Jiang Liu 1,2 email and Ji-De Wang 1,2,* email
1 School of Science, Xi'an Jiaotong University, 710049 Xi'an, P. R. China 2 School of Chemistry and Chemical Engineering, Xinjiang University, Key Laboratory of Oil and Gas Fine Chemicals, Ministry of Education, 830046 Urumqi, P. R. China
* Author to whom correspondence should be addressed.
Received: 11 January 2009; in revised form: 6 February 2009 / Accepted: 11 February 2009 / Published: 13 February 2009
PDF Full-text Download PDF Full-Text [168 KB, uploaded 17 February 2009 07:57 CET]
Abstract: A simple, efficient procedure for the one-pot Biginelli condensation reaction of aldehydes, β-ketoesters and urea or thiourea employing copper(II) sulfamate as a novel catalyst is described. Compared to the classical Biginelli reaction conditions, the present method has the advantages of good yields, short reaction times and experimental simplicity.
Keywords: Copper(II) sulfamate; Biginelli reaction; Dihydropyrimidinones

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Liu, C.-J.; Wang, J.-D. Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones. Molecules 2009, 14, 763-770.

AMA Style

Liu C-J, Wang J-D. Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones. Molecules. 2009; 14(2):763-770.

Chicago/Turabian Style

Liu, Chen-Jiang; Wang, Ji-De. 2009. "Copper(II) Sulfamate: An Efficient Catalyst for the One-Pot Synthesis of 3,4-Dihydropyrimidine-2(1H)-ones and thiones." Molecules 14, no. 2: 763-770.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert