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• Mohammat, MF.
• Shaameri, Z
• Hamzah, AS.
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• Mohammat, MF.
• Shaameri, Z
• Hamzah, AS.
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• Mohammat, MF.
• Shaameri, Z
• Hamzah, AS.

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Molecules 2009, 14(1), 250-256; doi:10.3390/molecules14010250

Article

Synthesis of 2,3-Dioxo-5-(substituted)arylpyrroles and Their 2-Oxo-5-aryl-3-hydrazone Pyrrolidine Derivatives

M. F. Mohammat, Z. Shaameri and A. S. Hamzah *

Organic Synthesis Laboratory, Institute of Science, Universiti Teknologi MARA (UiTM), 40450 Shah Alam, Selangor, Malaysia

* Author to whom correspondence should be addressed.

Received: 13 October 2008; in revised form: 21 November 2008 / Accepted: 2 December 2008 / Published: 7 January 2009

Download PDF Full-Text [119 KB, uploaded 7 January 2009 13:51 CET]

Abstract: Some novel2,3-dioxo-5-(substituted)arylpyrroles have been synthesized. Among these, pyrrolidine compound 1b was converted to 2,3-dioxo-5-aryl pyrrolidine 2b. Finally a set of hydrazone derivatives was obtained from the reaction of 2b with various hydrazine salts. The structures of all the new synthesized compounds were confirmed by elemental analyses, IR and ¹H-NMR spectra.

Keywords: Pyrrolidine; Hydrazine; Hydrazone; 2; 3-Dioxo-5-(substituted)arylpyrroles

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