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Molecules 2007, 12(9), 2123-2129; doi:10.3390/12092123
Communication

Synthesis of Ring-Contracted Erythromycin A Derivatives via Microwave-Assisted Intramolecular Transesterification

1, 1,* , 1, 1, 1, 2, 1 and 1,*
Received: 30 May 2007; in revised form: 16 August 2007 / Accepted: 24 August 2007 / Published: 30 August 2007
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Abstract: The synthesis of ring-contracted derivatives of erythromycin A via intramolecular transesterification under microwave irradiation of 8,9-anhydroerythromycin A 6,9-hemiketal and its derivatives is described. It was found that microwave irradiation could significantly improve the yields and shorten the reaction times under either solvent-containing (method A) or solvent-free (method B) conditions.
Keywords: Ring-contracted derivatives of erythromycin; transesterification; microwave irradiation Ring-contracted derivatives of erythromycin; transesterification; microwave irradiation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Bao, K.; Zhang, W.; Zhang, C.; Qu, Y.; Tian, L.; Wu, L.; Zhao, X.; Cheng, M. Synthesis of Ring-Contracted Erythromycin A Derivatives via Microwave-Assisted Intramolecular Transesterification. Molecules 2007, 12, 2123-2129.

AMA Style

Bao K, Zhang W, Zhang C, Qu Y, Tian L, Wu L, Zhao X, Cheng M. Synthesis of Ring-Contracted Erythromycin A Derivatives via Microwave-Assisted Intramolecular Transesterification. Molecules. 2007; 12(9):2123-2129.

Chicago/Turabian Style

Bao, Kai; Zhang, Weige; Zhang, Chuanliang; Qu, Yingwei; Tian, Liang; Wu, Lan; Zhao, Xiang; Cheng, Maosheng. 2007. "Synthesis of Ring-Contracted Erythromycin A Derivatives via Microwave-Assisted Intramolecular Transesterification." Molecules 12, no. 9: 2123-2129.


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