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A Study on 4-Acylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones
AbstractFive novel 3-alkyl-4-phenylacetylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) were synthesized by the reactions of 3-alkyl-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (1) with phenylacetyl chloride and characterized by elemental analyses and IR, 1HNMR, 13C-NMR and UV spectral data. The newly synthesized compounds 2 were titrated potentiometrically with tetrabutylammonium hydroxide in four non-aqueous solvents such as isopropyl alcohol, tert-butyl alcohol, acetonitrile and N,N-dimethylformamide, and the half-neutralization potential values and the corresponding pKa values were determined for all cases. In addition, these new compounds and five recently reported 3-alkyl-4-(pmethoxybenzoylamino)- 4,5-dihydro-1H-1,2,4-triazol-5-ones (3) were screened for their antioxidant activities.
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Alkan, M.; Yüksek, H.; İslamoğlu, F.; Bahçeci, S.; Calapoğlu, M.; Elmastaş, M.; Akşit, H.; Özdemir, M. A Study on 4-Acylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones. Molecules 2007, 12, 1805-1816.View more citation formats
Alkan M, Yüksek H, İslamoğlu F, Bahçeci S, Calapoğlu M, Elmastaş M, Akşit H, Özdemir M. A Study on 4-Acylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones. Molecules. 2007; 12(8):1805-1816.Chicago/Turabian Style
Alkan, Muzaffer; Yüksek, Haydar; İslamoğlu, Fatih; Bahçeci, Sule; Calapoğlu, Mustafa; Elmastaş, Mahfuz; Akşit, Hüseyin; Özdemir, Mustafa. 2007. "A Study on 4-Acylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones." Molecules 12, no. 8: 1805-1816.