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Molecules 2007, 12(7), 1447-1454; doi:10.3390/12071447
Article

Leufolins A and B, Potent Butyrylcholinesterase-inhibiting Flavonoid Glucosides from Leucas urticifolia

1, 1, 2, 1,* , 3, 3, 3 and 3
Received: 2 July 2007 / Revised: 12 July 2007 / Accepted: 12 July 2007 / Published: 19 July 2007
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Abstract

New flavonoidal glucosides leufolins A (1) and B (2), have been isolated from the ethyl acetate soluble fraction of the whole plants of Leucas urticifolia. Their structures were elucidated on the basis of extensive analysis of nuclear magnetic resonance (1D and 2D NMR) spectral data. Both of these compounds exhiited significant inhibitory potential against the enzyme butyrylcholinesterase.
Keywords: Leucas urticifolia; Lamiaceae; Leufolin A; Leufolin B; Butyrylcholinesterase; Leucas urticifolia; Lamiaceae; Leufolin A; Leufolin B; Butyrylcholinesterase; Inhibitory activity Leucas urticifolia; Lamiaceae; Leufolin A; Leufolin B; Butyrylcholinesterase; Leucas urticifolia; Lamiaceae; Leufolin A; Leufolin B; Butyrylcholinesterase; Inhibitory activity
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Noor, A.-T.; Fatima, I.; Ahmad, I.; Malik, A.; Afza, N.; Iqbal, L.; Latif, M.; Khan, S.B. Leufolins A and B, Potent Butyrylcholinesterase-inhibiting Flavonoid Glucosides from Leucas urticifolia. Molecules 2007, 12, 1447-1454.

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