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Molecules 2007, 12(5), 997-1005; doi:10.3390/12050997
Article

β-Orcinol Metabolites from the Lichen Hypotrachyna revoluta

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Received: 27 March 2007 / Revised: 7 May 2007 / Accepted: 11 May 2007 / Published: 12 May 2007
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Abstract

Four new β-orcinol metabolites, hypotrachynic acid (1), deoxystictic acid (2), cryptostictinolide (3) and 8 ́-methylconstictic acid (4) along with the metabolites 8 ́-methylstictic acid (5), 8 ́-methylmenegazziaic acid (6), stictic acid (7), 8 ́-ethylstictic acid (8) and atranorin (9), that have been previously described, were isolated for the first time from the tissue extracts of the lichen Hypotrachyna revoluta (Flörke) Hale. The structures of the new metabolites were elucidated on the basis of extensive spectroscopic analyses. Radical scavenging activity (RSA) of the metabolites isolated in adequate amounts, was evaluated using luminol chemiluminescence and comparison with Trolox®.
Keywords: Hypotrachyna revoluta; Hypotrachynic acid; Deoxystictic acid; Cryptostictinolide; 8΄-Methylconstictic acid; Radical scavenging activity Hypotrachyna revoluta; Hypotrachynic acid; Deoxystictic acid; Cryptostictinolide; 8΄-Methylconstictic acid; Radical scavenging activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Papadopoulou, P.; Tzakou, O.; Vagias, C.; Kefalas, P.; Roussis, V. β-Orcinol Metabolites from the Lichen Hypotrachyna revoluta. Molecules 2007, 12, 997-1005.

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