Molecules 2007, 12(5), 997-1005; doi:10.3390/12050997
Article

β-Orcinol Metabolites from the Lichen Hypotrachyna revoluta

Panagiota Papadopoulou 1 email, Olga Tzakou 1,* email, Constantinos Vagias 1 email, Panagiotis Kefalas 2 email and Vassilios Roussis 1 email
1 University of Athens, Department of Pharmacy, Division of Pharmacognosy and Chemistry of Natural Products, Panepistimioupoli Zographou, Athens, 157 71, Greece 2 Department of Food Quality and Chemistry of Naturals Products, Mediterranean Agronomic Institute of Chania, Alsyllion Agrokepiou, Chania, 73100, Crete, Greece
* Author to whom correspondence should be addressed.
Received: 27 March 2007; in revised form: 7 May 2007 / Accepted: 11 May 2007 / Published: 12 May 2007
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Abstract: Four new β-orcinol metabolites, hypotrachynic acid (1), deoxystictic acid (2), cryptostictinolide (3) and 8 ́-methylconstictic acid (4) along with the metabolites 8 ́-methylstictic acid (5), 8 ́-methylmenegazziaic acid (6), stictic acid (7), 8 ́-ethylstictic acid (8) and atranorin (9), that have been previously described, were isolated for the first time from the tissue extracts of the lichen Hypotrachyna revoluta (Flörke) Hale. The structures of the new metabolites were elucidated on the basis of extensive spectroscopic analyses. Radical scavenging activity (RSA) of the metabolites isolated in adequate amounts, was evaluated using luminol chemiluminescence and comparison with Trolox®.
Keywords: Hypotrachyna revoluta; Hypotrachynic acid; Deoxystictic acid; Cryptostictinolide; 8΄-Methylconstictic acid; Radical scavenging activity

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MDPI and ACS Style

Papadopoulou, P.; Tzakou, O.; Vagias, C.; Kefalas, P.; Roussis, V. β-Orcinol Metabolites from the Lichen Hypotrachyna revoluta. Molecules 2007, 12, 997-1005.

AMA Style

Papadopoulou P, Tzakou O, Vagias C, Kefalas P, Roussis V. β-Orcinol Metabolites from the Lichen Hypotrachyna revoluta. Molecules. 2007; 12(5):997-1005.

Chicago/Turabian Style

Papadopoulou, Panagiota; Tzakou, Olga; Vagias, Constantinos; Kefalas, Panagiotis; Roussis, Vassilios. 2007. "β-Orcinol Metabolites from the Lichen Hypotrachyna revoluta." Molecules 12, no. 5: 997-1005.

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