Molecules 2007, 12(5), 932-945; doi:10.3390/12050932
Article

Evaluation of the Antimicrobial and Antioxidant Activities of Origanum dictamnus Extracts before and after Encapsulation in Liposomes

1email, 1,* email, 2email and 3email
Received: 21 March 2007; in revised form: 25 April 2007 / Accepted: 1 May 2007 / Published: 2 May 2007
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The antioxidant and antimicrobial activity of methanol or dichloromethane extracts of O. dictamnus, produced from wild and organic cultivated specimens, were determined. The Rancimat and malondialdehyde (MDA) by HPLC methods were used to measure the antioxidant action, in comparison with that of the common commercial antioxidants butylated hydroxytoluene (BHT) and α-tocopherol. The extracts that presented high antioxidant activity were encapsulated in liposomes and their antioxidant action was again estimated using differential scanning calorimetry (DSC). Thermaloxidative decomposition of the samples (pure liposomes and encapsulated extracts) and the modification of the main transition temperature for the lipid mixture and the splitting of the calorimetric peak in the presence of the antioxidants were also studied by the DSC method. All extracts showed antioxidant and antimicrobial activities. Their action proved superior to α-tocopherol. The methanol extract of organic cultivated O. dictamnus (240 ppm) showed higher activity than butylated hydroxytoluene. After encapsulation in liposomes the antioxidant as well as antimicrobial activities proved to be higher than those of the same extracts in pure form.
Keywords: Origanum dictamnus;liposomes;antimicrobial activity;antioxidant activity;DSC.
PDF Full-text Download PDF Full-Text [103 KB, uploaded 18 June 2014 19:27 CEST]

Export to BibTeX |
EndNote


MDPI and ACS Style

Gortzi, O.; Lala, S.; Chinou, I.; Tsaknis, J. Evaluation of the Antimicrobial and Antioxidant Activities of Origanum dictamnus Extracts before and after Encapsulation in Liposomes. Molecules 2007, 12, 932-945.

AMA Style

Gortzi O, Lala S, Chinou I, Tsaknis J. Evaluation of the Antimicrobial and Antioxidant Activities of Origanum dictamnus Extracts before and after Encapsulation in Liposomes. Molecules. 2007; 12(5):932-945.

Chicago/Turabian Style

Gortzi, Olga; Lala, Stavros; Chinou, Ioanna; Tsaknis, John. 2007. "Evaluation of the Antimicrobial and Antioxidant Activities of Origanum dictamnus Extracts before and after Encapsulation in Liposomes." Molecules 12, no. 5: 932-945.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert