C(aryl)-O Bond Formation from Aryl Methanesulfonates via Consecutive Deprotection and SNAr Reactions with Aryl Halides in an Ionic Liquid

doi:10.3390/12040861

This article is

freely available
re-usable

Molecules 2007, 12(4), 861-867; doi:10.3390/12040861

Communication

C(aryl)-O Bond Formation from Aryl Methanesulfonates via Consecutive Deprotection and S_NAr Reactions with Aryl Halides in an Ionic Liquid

Hui Xu and Yang Chen*

College of Science, Northwest A and F University, Yangling 712100, P.R. China

* Author to whom correspondence should be addressed.

Received: 28 March 2007; in revised form: 19 April 2007 / Accepted: 20 April 2007 / Published: 30 April 2007

Download PDF Full-Text [70 KB, uploaded 2 October 2008 11:53 CEST]

Abstract: An efficient K₃PO₄-mediated synthesis of unsymmetrical diaryl ethers using the ionic liquid [Bmim]BF₄ (1-butyl-3-methylimidazolium tetrafluoroborate) as solvent has been developed. The procedure involves consecutive deprotection of aryl methane-sulfonates and a nucleophilic aromatic substitution (S_NAr) with activated aryl halides.

Keywords: C(aryl)-O bond; aryl methanesulfonates; nucleophilic aromatic substitution; diaryl ethers; ionic liquid

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Xu, H.; Chen, Y. C(aryl)-O Bond Formation from Aryl Methanesulfonates via Consecutive Deprotection and S_NAr Reactions with Aryl Halides in an Ionic Liquid. Molecules 2007, 12, 861-867.

AMA Style

Xu H, Chen Y. C(aryl)-O Bond Formation from Aryl Methanesulfonates via Consecutive Deprotection and S_NAr Reactions with Aryl Halides in an Ionic Liquid. Molecules. 2007; 12(4):861-867.

Chicago/Turabian Style

Xu, Hui; Chen, Yang. 2007. "C(aryl)-O Bond Formation from Aryl Methanesulfonates via Consecutive Deprotection and S_NAr Reactions with Aryl Halides in an Ionic Liquid." Molecules 12, no. 4: 861-867.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert