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Molecules 2007, 12(2), 245-254; doi:10.3390/12020245
Article

Synthesis, Characterization and AntibacterialActivity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid

1
, 1,* , 2
, 1
 and 3
Received: 10 February 2007; in revised form: 20 February 2007 / Accepted: 21 February 2007 / Published: 22 February 2007
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Abstract: A series of eight new azomethine derivatives were synthesized by reacting 2-formylphenoxyacetic acid with aromatic amines. The chemical structures of these compounds were confirmed by means of 1H-NMR, 13C-NMR, MS and elemental analysis. The compounds were assayed by the disc diffusion method for antibacterial against Staphylococcus aureus and Escherichia coli. Among the compounds tested, 2a, 2b, 2e, 2g and 2h exhibited good antibacterial activity, almost equal to that of Ciprofloxacin used as standard.
Keywords: 2-Formylphenoxyacetic acid; picoline;N-phenylhydrazine; p-toluidine;o bromobenzylamine;2; 3-dichloroaniline; p-aminoacetanilide; imidazole; thiazole; antibacterial activity 2-Formylphenoxyacetic acid; picoline; N-phenylhydrazine; p-toluidine; o bromobenzylamine; 2; 3-dichloroaniline; p-aminoacetanilide; imidazole; thiazole; antibacterial activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Iqbal, A.; Siddiqui, H.L.; Ashraf, C.M.; Ahmad, M.; Weaver, G.W. Synthesis, Characterization and AntibacterialActivity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid. Molecules 2007, 12, 245-254.

AMA Style

Iqbal A, Siddiqui HL, Ashraf CM, Ahmad M, Weaver GW. Synthesis, Characterization and AntibacterialActivity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid. Molecules. 2007; 12(2):245-254.

Chicago/Turabian Style

Iqbal, Amjid; Siddiqui, Hamid L.; Ashraf, C. M.; Ahmad, Matloob; Weaver, George W. 2007. "Synthesis, Characterization and AntibacterialActivity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid." Molecules 12, no. 2: 245-254.


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