Molecules 2007, 12(2), 245-254; doi:10.3390/12020245
Article

Synthesis, Characterization and AntibacterialActivity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid

Amjid Iqbal 1 email, Hamid Latif Siddiqui 1,* email, C. M. Ashraf 2 email, Matloob Ahmad 1 email and George W. Weaver 3 email
1 Institute of Chemistry, University of the Punjab, Lahore-54590, Pakistan 2 Department of Chemistry, Forman Christian College (A Chartered University) Lahore-54600, Pakistan 3 Department of Chemistry, Loughborough University, Loughborough, LE 11 3TU, UK
* Author to whom correspondence should be addressed.
Received: 10 February 2007; in revised form: 20 February 2007 / Accepted: 21 February 2007 / Published: 22 February 2007
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Abstract: A series of eight new azomethine derivatives were synthesized by reacting 2-formylphenoxyacetic acid with aromatic amines. The chemical structures of these compounds were confirmed by means of 1H-NMR, 13C-NMR, MS and elemental analysis. The compounds were assayed by the disc diffusion method for antibacterial against Staphylococcus aureus and Escherichia coli. Among the compounds tested, 2a, 2b, 2e, 2g and 2h exhibited good antibacterial activity, almost equal to that of Ciprofloxacin used as standard.
Keywords: 2-Formylphenoxyacetic acid; picoline;N-phenylhydrazine; p-toluidine;o bromobenzylamine;2; 3-dichloroaniline; p-aminoacetanilide; imidazole; thiazole; antibacterial activity

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MDPI and ACS Style

Iqbal, A.; Siddiqui, H.L.; Ashraf, C.M.; Ahmad, M.; Weaver, G.W. Synthesis, Characterization and AntibacterialActivity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid. Molecules 2007, 12, 245-254.

AMA Style

Iqbal A, Siddiqui HL, Ashraf CM, Ahmad M, Weaver GW. Synthesis, Characterization and AntibacterialActivity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid. Molecules. 2007; 12(2):245-254.

Chicago/Turabian Style

Iqbal, Amjid; Siddiqui, Hamid L.; Ashraf, C. M.; Ahmad, Matloob; Weaver, George W. 2007. "Synthesis, Characterization and AntibacterialActivity of Azomethine Derivatives Derived from 2-Formylphenoxyacetic Acid." Molecules 12, no. 2: 245-254.

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