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Two New Triterpenoids from Photinia serrulata
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P. R. China
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Beijing 100094, P. R. China
College of Sciences, Northwest A & F University, Yangling 712100, P. R. China
* Authors to whom correspondence should be addressed.
Received: 24 November 2007; in revised form: 11 December 2007 / Accepted: 11 December 2007 / Published: 20 December 2007
Abstract: Two new triterpenoids, 2α,3β,11α,13β-tetrahydroxy-12-ketooleanan-28-oic acid(1) and 3β-hydroxy-12-keto-9(11)-ursen-28,13β-olide (2) were isolated from the leaves ofPhotinia serrulata. Their structures were identified by spectral methods. Compounds 1 and2 were assessed for cytotoxic activity against three human tumor cell lines (A-549, HCT-8,and BEL-7402), and they showed no cytotoxic effects at concentrations up to 5μg/mL.
Keywords: Photinia serrulata; Rosaceae; triterpenoids; cytotoxic activity
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Song, Y.; Wang, Y.; Lu, Q.; Gao, J.; Bi, M.; Cheng, Y. Two New Triterpenoids from Photinia serrulata. Molecules 2007, 12, 2599-2604.
Song Y, Wang Y, Lu Q, Gao J, Bi M, Cheng Y. Two New Triterpenoids from Photinia serrulata. Molecules. 2007; 12(12):2599-2604.
Song, Yaling; Wang, Yuehu; Lu, Qing; Gao, Jinming; Bi, Minggang; Cheng, Yongxian. 2007. "Two New Triterpenoids from Photinia serrulata." Molecules 12, no. 12: 2599-2604.