Molecules 2007, 12(1), 1-12; doi:10.3390/12010001

Salicylanilide Acetates: Synthesis and Antibacterial Evaluation

1,* email, 1, 2, 1, 1, 1, 3 and 4
Received: 27 October 2008; in revised form: 3 December 2008 / Accepted: 4 December 2008 / Published: 1 January 2008
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: A new series of salicylanilide acetates was synthesized and evaluated for their in vitro antifungal and antituberculotic activity. Some of the evaluated compounds possessed comparable or better antifungal activity than a fluconazole standard. All these compounds exhibited very good potential and their in vitro activity against drug resistant and sensitive clinical isolates of Mycobacteria were found to be equivalent or better than a standard of isoniazide, a well-known first-line drug for tuberculosis treatment.
Keywords: Salicylanilide acetates; in vitro antifungal activity; in vitro antimycobacterial activity; lipophilicity determination; cytotoxicity; structure-activity relationships
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MDPI and ACS Style

Vinsova, J.; Imramovsky, A.; Buchta, V.; Ceckova, M.; Dolezal, M.; Staud, F.; Jampilek, J.; Kaustova, J. Salicylanilide Acetates: Synthesis and Antibacterial Evaluation. Molecules 2007, 12, 1-12.

AMA Style

Vinsova J, Imramovsky A, Buchta V, Ceckova M, Dolezal M, Staud F, Jampilek J, Kaustova J. Salicylanilide Acetates: Synthesis and Antibacterial Evaluation. Molecules. 2007; 12(1):1-12.

Chicago/Turabian Style

Vinsova, Jarmila; Imramovsky, Ales; Buchta, Vladimir; Ceckova, Martina; Dolezal, Martin; Staud, Frantisek; Jampilek, Josef; Kaustova, Jarmila. 2007. "Salicylanilide Acetates: Synthesis and Antibacterial Evaluation." Molecules 12, no. 1: 1-12.

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