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Molecules 2007, 12(1), 13-24; doi:10.3390/12010013
Article

Synthesis, Characterization, and Saccharide Binding Studies of Bile Acid − Porphyrin Conjugates

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Received: 17 November 2006 / Revised: 2 January 2007 / Accepted: 4 January 2007 / Published: 5 January 2007
(This article belongs to the Special Issue Bile Acids)
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Abstract

Synthesis and characterization of bile acid-porphyrin conjugates (BAPs) are reported. Binding of saccharides with BAPs in aqueous methanol was studied by monitoring changes in the visible absorption spectral of the porphyrin-moieties. Although these studies clearly showed absorbance changes, suggesting quite high if non-selective binding, the mass spectral studies do not unambiguously support these results.
Keywords: Bile acids; porphyrin; saccharide; visible spectroscopy; 1H-NMR; ESI MS. Bile acids; porphyrin; saccharide; visible spectroscopy; 1H-NMR; ESI MS.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Koivukorpi, J.; Sievänen, E.; Kolehmainen, E.; Král, V. Synthesis, Characterization, and Saccharide Binding Studies of Bile Acid − Porphyrin Conjugates. Molecules 2007, 12, 13-24.

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