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Molecules 2006, 11(9), 726-730; doi:10.3390/11090726

Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts

1,*  and 2
1 Department of Chemistry, Faculty of Natural Sciences, Mathematics and Education, University of Split, N. Tesle 12, 21 000 Split, Croatia 2 Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10 000 Zagreb, Croatia
* Author to whom correspondence should be addressed.
Received: 28 July 2006 / Revised: 30 August 2006 / Accepted: 21 September 2006 / Published: 28 September 2006
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The synthesis of racemic and enantiomerically pure N-p-methylbenzyl-3- and N-p-chlorobenzylbenzamidoquinuclidinium bromides (6-8 and 9-11, respectively) is described. These compounds were prepared from racemic or enantiomerically pure 3-benzamidoquinuclidines 3-5 using the appropriate quaternization reagents: p-methyl- benzyl bromide (1) and p-chlorobenzyl bromide (2).
Keywords: Quinuclidine; N-quaternary salts; quaternization Quinuclidine; N-quaternary salts; quaternization
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Odzak, R.; Tomic, S. Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts. Molecules 2006, 11, 726-730.

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