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Molecules 2006, 11(9), 726-730; doi:10.3390/11090726

Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts

1,*  and 2
1 Department of Chemistry, Faculty of Natural Sciences, Mathematics and Education, University of Split, N. Tesle 12, 21 000 Split, Croatia 2 Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10 000 Zagreb, Croatia
* Author to whom correspondence should be addressed.
Received: 28 July 2006 / Revised: 30 August 2006 / Accepted: 21 September 2006 / Published: 28 September 2006
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The synthesis of racemic and enantiomerically pure N-p-methylbenzyl-3- and N-p-chlorobenzylbenzamidoquinuclidinium bromides (6-8 and 9-11, respectively) is described. These compounds were prepared from racemic or enantiomerically pure 3-benzamidoquinuclidines 3-5 using the appropriate quaternization reagents: p-methyl- benzyl bromide (1) and p-chlorobenzyl bromide (2).
Keywords: Quinuclidine; N-quaternary salts; quaternization Quinuclidine; N-quaternary salts; quaternization
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Odzak, R.; Tomic, S. Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts. Molecules 2006, 11, 726-730.

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