Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts

doi:10.3390/11090726

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Molecules 2006, 11(9), 726-730; doi:10.3390/11090726

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Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts

Renata Odzak^1,* and Srdjanka Tomic²

¹ Department of Chemistry, Faculty of Natural Sciences, Mathematics and Education, University of Split, N. Tesle 12, 21 000 Split, Croatia ² Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10 000 Zagreb, Croatia

* Author to whom correspondence should be addressed.

Received: 28 July 2006; in revised form: 30 August 2006 / Accepted: 21 September 2006 / Published: 28 September 2006

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Abstract: The synthesis of racemic and enantiomerically pure N-p-methylbenzyl-3- and N-p-chlorobenzylbenzamidoquinuclidinium bromides (6-8 and 9-11, respectively) is described. These compounds were prepared from racemic or enantiomerically pure 3-benzamidoquinuclidines 3-5 using the appropriate quaternization reagents: p-methyl- benzyl bromide (1) and p-chlorobenzyl bromide (2).

Keywords: Quinuclidine; N-quaternary salts; quaternization

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MDPI and ACS Style

Odzak, R.; Tomic, S. Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts. Molecules 2006, 11, 726-730.

AMA Style

Odzak R, Tomic S. Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts. Molecules. 2006; 11(9):726-730.

Chicago/Turabian Style

Odzak, Renata; Tomic, Srdjanka. 2006. "Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts." Molecules 11, no. 9: 726-730.

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