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Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts
Department of Chemistry, Faculty of Natural Sciences, Mathematics and Education, University of
Split, N. Tesle 12, 21 000 Split, Croatia
Department of Chemistry, Faculty of Science, University of Zagreb, Horvatovac 102a, 10 000
* Author to whom correspondence should be addressed.
Received: 28 July 2006; in revised form: 30 August 2006 / Accepted: 21 September 2006 / Published: 28 September 2006
Abstract: The synthesis of racemic and enantiomerically pure N-p-methylbenzyl-3- and N-p-chlorobenzylbenzamidoquinuclidinium bromides (6-8 and 9-11, respectively) is described. These compounds were prepared from racemic or enantiomerically pure 3-benzamidoquinuclidines 3-5 using the appropriate quaternization reagents: p-methyl- benzyl bromide (1) and p-chlorobenzyl bromide (2).
Keywords: Quinuclidine; N-quaternary salts; quaternization
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Odzak, R.; Tomic, S. Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts. Molecules 2006, 11, 726-730.
Odzak R, Tomic S. Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts. Molecules. 2006; 11(9):726-730.
Odzak, Renata; Tomic, Srdjanka. 2006. "Synthesis of New N-Quaternary-3-benzamidoquinuclidinium Salts." Molecules 11, no. 9: 726-730.