CiteULike
Connotea
Facebook
Mendeley
Twitter
This article is- freely available
- re-usable
Molecules 2006, 11(8), 615-626; doi:10.3390/11080615
Article
Synthesis of Conformationally Constrained Aryl- or Heteroarylpiperazinyl Derivatives of Selected Imides as 5-HT1A Receptor Ligands
Department of Medical Chemistry, Medical University, 3 Oczki St., 02-007 Warsaw, Poland
* Author to whom correspondence should be addressed.
Received: 14 June 2006; in revised form: 3 August 2006 / Accepted: 11 August 2006 / Published: 23 August 2006
Download PDF Full-Text [90 KB, uploaded 20 June 2008 16:50 CET]
Abstract: The preparation of a number of cyclic imide 5-HT1A receptor ligandderivatives has been described. Their structures were conformationally constrained byintroducing rigid linkers containing unsaturated bonds or aromatic benzene rings. Thesecompounds are expected to possess anxiolytic and antidepressant activity.
Keywords: Conformational constraints; cis- and trans-2-butene derivatives; 1; 2- bismethylbenzene derivatives; imides; 5-HT1A receptor ligands.
Article Statistics
Click here to load and display the download statistics.Cite This Article
MDPI and ACS Style
Kossakowski, J.; Krawiecka, M.; Kuran, B. Synthesis of Conformationally Constrained Aryl- or Heteroarylpiperazinyl Derivatives of Selected Imides as 5-HT1A Receptor Ligands. Molecules 2006, 11, 615-626.
AMA StyleKossakowski J., Krawiecka M., Kuran B. Synthesis of Conformationally Constrained Aryl- or Heteroarylpiperazinyl Derivatives of Selected Imides as 5-HT1A Receptor Ligands. Molecules. 2006; 11(8):615-626.
Chicago/Turabian StyleKossakowski, Jerzy; Krawiecka, Mariola; Kuran, Bożena. 2006. "Synthesis of Conformationally Constrained Aryl- or Heteroarylpiperazinyl Derivatives of Selected Imides as 5-HT1A Receptor Ligands." Molecules 11, no. 8: 615-626.
Molecules
EISSN 1420-3049
Published by MDPI Publishing, Basel, Switzerland
RSS
E-Mail Table of Contents Alert