Molecules 2006, 11(4), 257-262; doi:10.3390/11040257
Communication

Isolation and Biological Activity of New and Known Diterpenoids From Sideritis stricta Boiss. & Heldr.

Turgut Kilicemail
Balikesir University, Faculty of Arts and Sciences, Department of Chemistry, 10100, Balikesir, Turkey
Received: 28 October 2005; in revised form: 20 February 2006 / Accepted: 21 February 2006 / Published: 29 March 2006
PDF Full-text Download PDF Full-Text [55 KB, uploaded 20 June 2008 16:50 CEST]
Abstract: Nine known and one new ent-kaurene diterpenoid were isolated from the acetone extract of Sideritis stricta Boiss & Heldr. The new compound, identified as ent-1β-hydroxy-7α-acetyl-15β,16β-epoxykaurane (1) by IR, 1D and 2D NMR techniques and mass spectra, was isolated along with sideroxol (2), 7-acetyl sideroxol (3), 7-epicandicandiol (4), linearol (5), ent-7α,15β,18-trihydroxy-kaur-16-ene (6), ent-7α-acetyl,15,18-dihydroxy-kaur-16-ene (7), foliol (8), sideridiol (9) and siderol (10). The antibacterial and antifungal activities of these compounds and the whole crude acetone extract were evaluated against E. coli, S. aureus, K. pneumeonia and C. albicans.
Keywords: Kaurene; Diterpenoids; Sideritis stricta; Lamiaceae; Antibacterial Activity

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Kilic, T. Isolation and Biological Activity of New and Known Diterpenoids From Sideritis stricta Boiss. & Heldr.. Molecules 2006, 11, 257-262.

AMA Style

Kilic T. Isolation and Biological Activity of New and Known Diterpenoids From Sideritis stricta Boiss. & Heldr.. Molecules. 2006; 11(4):257-262.

Chicago/Turabian Style

Kilic, Turgut. 2006. "Isolation and Biological Activity of New and Known Diterpenoids From Sideritis stricta Boiss. & Heldr.." Molecules 11, no. 4: 257-262.

Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert