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Molecules 2006, 11(12), 968-977; doi:10.3390/11120968
Communication

Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid

1,* , 1, 1, 2 and 2
Received: 25 October 2006; in revised form: 8 December 2006 / Accepted: 15 December 2006 / Published: 18 December 2006
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Abstract: In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary results indicate that hyperbranched architectures could represent a peculiar molecular requisite for the development of new antiviral lead compounds.
Keywords: Hyperbranched polymers; AB2 monomers; DHICA; HIV-1; antiviral agents. Hyperbranched polymers; AB2 monomers; DHICA; HIV-1; antiviral agents.
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Sechi, M.; Casu, F.; Campesi, I.; Fiori, S.; Mariani, A. Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid. Molecules 2006, 11, 968-977.

AMA Style

Sechi M, Casu F, Campesi I, Fiori S, Mariani A. Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid. Molecules. 2006; 11(12):968-977.

Chicago/Turabian Style

Sechi, Mario; Casu, Fabio; Campesi, Ilaria; Fiori, Stefano; Mariani, Alberto. 2006. "Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid." Molecules 11, no. 12: 968-977.


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