Next Article in Journal
CuCl2-catalyzed One-pot Formation of Tetrahydroquinolines from N-Methyl-N-alkylanilines and Vinyl Ethers in the Presence of t-Butylhydroperoxide
Previous Article in Journal
Synthesis of (R)-2-(Benzyloxy)-tetrahydro-5,5-dimethylfuran by a New Oxidative Rearrangement
Article Menu

Export Article

Open AccessCommunication
Molecules 2006, 11(12), 968-977; https://doi.org/10.3390/11120968

Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid

1
Dipartimento Farmaco Chimico Tossicologico, Università di Sassari, Via Muroni 23/A, 07100 Sassari, Italy
2
Dipartimento di Chimica, Università di Sassari and local INSTM Research Unit, Via Vienna 2, 07100 Sassari, Italy
*
Author to whom correspondence should be addressed.
Received: 25 October 2006 / Revised: 8 December 2006 / Accepted: 15 December 2006 / Published: 18 December 2006
Full-Text   |   PDF [61 KB, uploaded 18 June 2014]   |  

Abstract

In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary results indicate that hyperbranched architectures could represent a peculiar molecular requisite for the development of new antiviral lead compounds. View Full-Text
Keywords: Hyperbranched polymers; AB2 monomers; DHICA; HIV-1; antiviral agents. Hyperbranched polymers; AB2 monomers; DHICA; HIV-1; antiviral agents.
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Sechi, M.; Casu, F.; Campesi, I.; Fiori, S.; Mariani, A. Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid. Molecules 2006, 11, 968-977.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top