Next Article in Journal
Electrochemical Behavior and Antioxidant and Prooxidant Activity of Natural Phenolics
Previous Article in Journal
Improving the Quality of Published Chemical Names with Nomenclature Software
Molecules 2006, 11(11), 929-939; doi:10.3390/11110929

Reactivity of 4-tert-Butyldimethylsiloxy-1,2,3,6-tetrahydropyridines with Hydrazines

, * , ,  and
Laboratorio de Química Orgánica y Farmacéutica, Facultad de Farmacia, Campus Miguel de Unamuno, 37007 Salamanca, Spain
* Author to whom correspondence should be addressed.
Received: 2 November 2006 / Revised: 29 November 2006 / Accepted: 29 November 2006 / Published: 30 November 2006
View Full-Text   |   Download PDF [91 KB, uploaded 18 June 2014]   |  


The reactivity of 6-(nitrophenyl or trimethoxyphenyl)-4-tert-butyldimethyl- siloxy-1,2,3,6-tetrahydropyridine derivatives with hydrazines under acid conditions is described. The structure of the products isolated − hydrazones, pyrazolines or pyridazinones − depended on the conditions used. In addition, a systematic study of the reaction outcomes was carried out by introducing variations on the substituents of the tetrahydropyridine ring.
Keywords: Siloxy-1; 2; 3; 6-tetrahydropyridines; hydrazones; pyrazolines; pyridazinones. Siloxy-1; 2; 3; 6-tetrahydropyridines; hydrazones; pyrazolines; pyridazinones.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote |
MDPI and ACS Style

Figueroa, J.; Caballero, E.; Puebla, P.; Tomé, F.; Medarde, M. Reactivity of 4-tert-Butyldimethylsiloxy-1,2,3,6-tetrahydropyridines with Hydrazines. Molecules 2006, 11, 929-939.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert