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Synthesis of 2,4,6-Tri-substituted-1,3,5-Triazines
CQFM, Departamento de Engenharia Química, Instituto Superior Técnico, 1049-001 Lisboa, Portugal
REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 2829-516 Caparica, Portugal
* Author to whom correspondence should be addressed.
Received: 21 June 2005; in revised form: 8 September 2005 / Accepted: 8 September 2005 / Published: 31 January 2006
Abstract: Several specific synthetic protocols were developed for the preparation from cyanuric chloride of a range of symmetric and non-symmetric di- and tri-substituted 1,3,5-triazines containing alkyl, aromatic, hindered, chiral and achiral hydroxyalkyl, ester and imidazole groups via sequential nucleophilic substitution of the C-Cl bond by C-O, C-N and C-S bonds.
Keywords: Cyanuric chloride; s-triazine; 1; 3; 5-triazine; melamine derivatives.
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Afonso, C.A.M.; Lourenco, N.M.T.; Rosatella, A.A. Synthesis of 2,4,6-Tri-substituted-1,3,5-Triazines. Molecules 2006, 11, 81-102.
Afonso CAM, Lourenco NMT, Rosatella AA. Synthesis of 2,4,6-Tri-substituted-1,3,5-Triazines. Molecules. 2006; 11(1):81-102.
Afonso, Carlos A.M.; Lourenco, Nuno M.T.; Rosatella, Andreia A. 2006. "Synthesis of 2,4,6-Tri-substituted-1,3,5-Triazines." Molecules 11, no. 1: 81-102.