Next Article in Journal / Special Issue
Dakin-West Trick in the Design of Novel 2-Alkyl(aralkyl) Derivatives of Oxazolo[3,2-a]pyridines
Previous Article in Journal / Special Issue
Studies Towards the Total Synthesis of Di- and Sesterterpenes with Dicyclopenta[a,d]cyclooctane Skeletons. Three-component Approach to the A/B Rings Building Block
Molecules 2005, 10(9), 1101-1108; doi:10.3390/10091101
Article

The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles

, , ,  and *
Received: 23 April 2005 / Accepted: 30 September 2005 / Published: 30 September 2005
Download PDF [225 KB, uploaded 18 June 2014]

Abstract

The tert-amino reaction effect was examined. A new method to synthesize spiro heterocycles is presented. It was shown that the “tert-amino effect” could be applied to the formation of spiro-fused heterocycles. The formation of spiro compounds proceeds in most cases in good yields in a one-pot reaction.
Keywords: Tert-amino effect; cyclization; spiro compounds; Knoevenagel condensation; 1; 2; 3-thiadiazole; pyrazole; quinoline Tert-amino effect; cyclization; spiro compounds; Knoevenagel condensation; 1; 2; 3-thiadiazole; pyrazole; quinoline
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

D’yachenko, E.; Glukhareva, T.; Dyudya, L.; Eltsov, O.; Morzherin, Y. The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles. Molecules 2005, 10, 1101-1108.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

Cited By

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert