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Molecules 2005, 10(9), 1101-1108; doi:10.3390/10091101
Article

The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles

, , ,  and *
Received: 23 April 2005; Accepted: 30 September 2005 / Published: 30 September 2005
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Abstract: The tert-amino reaction effect was examined. A new method to synthesize spiro heterocycles is presented. It was shown that the “tert-amino effect” could be applied to the formation of spiro-fused heterocycles. The formation of spiro compounds proceeds in most cases in good yields in a one-pot reaction.
Keywords: Tert-amino effect; cyclization; spiro compounds; Knoevenagel condensation; 1; 2; 3-thiadiazole; pyrazole; quinoline Tert-amino effect; cyclization; spiro compounds; Knoevenagel condensation; 1; 2; 3-thiadiazole; pyrazole; quinoline
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

D’yachenko, E.; Glukhareva, T.; Dyudya, L.; Eltsov, O.; Morzherin, Y. The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles. Molecules 2005, 10, 1101-1108.

AMA Style

D’yachenko E, Glukhareva T, Dyudya L, Eltsov O, Morzherin Y. The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles. Molecules. 2005; 10(9):1101-1108.

Chicago/Turabian Style

D’yachenko, E.; Glukhareva, T.; Dyudya, L.; Eltsov, O.; Morzherin, Y. 2005. "The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles." Molecules 10, no. 9: 1101-1108.


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