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Molecules 2005, 10(9), 1101-1108; doi:10.3390/10091101

The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles

Department of Technology for Organic Synthesis (TOSLab), Urals State Technical University, Russia
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Received: 23 April 2005 / Accepted: 30 September 2005 / Published: 30 September 2005
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Abstract

The tert-amino reaction effect was examined. A new method to synthesize spiro heterocycles is presented. It was shown that the “tert-amino effect” could be applied to the formation of spiro-fused heterocycles. The formation of spiro compounds proceeds in most cases in good yields in a one-pot reaction.
Keywords: Tert-amino effect; cyclization; spiro compounds; Knoevenagel condensation; 1; 2; 3-thiadiazole; pyrazole; quinoline Tert-amino effect; cyclization; spiro compounds; Knoevenagel condensation; 1; 2; 3-thiadiazole; pyrazole; quinoline
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

D’yachenko, E.; Glukhareva, T.; Dyudya, L.; Eltsov, O.; Morzherin, Y. The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles. Molecules 2005, 10, 1101-1108.

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