Studies on the Synthesis and Reactivity of Novel Benzofuran-2-yl-[3-Methyl-3-Phenylcyclobutyl] Methanones and their Antimicrobial Activity

doi:10.3390/10070747

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Molecules 2005, 10(7), 747-754; doi:10.3390/10070747

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Studies on the Synthesis and Reactivity of Novel Benzofuran-2-yl-[3-Methyl-3-Phenylcyclobutyl] Methanones and their Antimicrobial Activity

Murat Koca ¹, Misir Ahmedzade ¹, Alaaddin Çukurovali ¹^,* and Cavit Kazaz ²

¹ Firat University, Faculty of Arts and Sciences, Chemistry Department, 23119 Elazig, Turkey ² Ataturk University, Faculty of Arts and Sciences, Chemistry Department, Erzurum, Turkey

* Author to whom correspondence should be addressed.

Received: 7 January 2004; in revised form: 10 February 2005 / Accepted: 15 February 2005 / Published: 31 August 2005

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Abstract: Preparation in excellent yields of cyclobutyl benzofuran-2-yl- and naphthofuran- 2-yl-ketones, the corresponding ketoximes and thiosemicarbazones, ether derivatives of the ketoximes and thiazoles derived from the thiosemicarbazones are described. Two of the synthesized compounds have been tested against eight different microorganisms and found to be active against some of the species studied.

Keywords: Furans; cyclobutane; oxime; thiazole; thiosemicarbazone.

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MDPI and ACS Style

Koca, M.; Ahmedzade, M.; Çukurovali, A.; Kazaz, C. Studies on the Synthesis and Reactivity of Novel Benzofuran-2-yl-[3-Methyl-3-Phenylcyclobutyl] Methanones and their Antimicrobial Activity. Molecules 2005, 10, 747-754.

AMA Style

Koca M., Ahmedzade M., Çukurovali A., Kazaz C. Studies on the Synthesis and Reactivity of Novel Benzofuran-2-yl-[3-Methyl-3-Phenylcyclobutyl] Methanones and their Antimicrobial Activity. Molecules. 2005; 10(7):747-754.

Chicago/Turabian Style

Koca, Murat; Ahmedzade, Misir; Çukurovali, Alaaddin; Kazaz, Cavit. 2005. "Studies on the Synthesis and Reactivity of Novel Benzofuran-2-yl-[3-Methyl-3-Phenylcyclobutyl] Methanones and their Antimicrobial Activity." Molecules 10, no. 7: 747-754.

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