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Molecules 2005, 10(2), 360-366; doi:10.3390/10020360
Article

Synthesis and X-ray Structure of a New Pyrrolo[1,2-b]-pyridazine Derivative

1,* , 2, 2, 2 and 2
1 Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa 2 Centre of Organic Chemistry “C. D. Nenitzescu”, Romanian Academy, Spl. Independentei 202B,Bucharest 060023, Romania
* Author to whom correspondence should be addressed.
Received: 26 November 2004 / Accepted: 16 December 2004 / Published: 28 February 2005
(This article belongs to the Special Issue Sulfur-Nitrogen Heterocycles)
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Abstract

The synthesis, characterization and X-ray crystal structure of 2-(4-chloro-phenyl)-7-methylpyrrolo[1,2-b]pyridazine are reported. The compound crystallizes in thespace group P21/c (No.14) with a =3.8568(1), b = 11.0690(3), c = 26.4243(7) å, β =92.777(1)° and Z = 4. Accurate molecular parameters for the novel heterocyclic systemwere obtained from intensity data collected at 113K. The molecule assumes a planarconformation in the crystal and the packing is based on π-π stacking with interplanarspacing 3.400 å, typical of aromatic molecules with potential for displaying usefuloptical properties.
Keywords: Pyrrolo[1; 2-b]pyridazine; crystal structure; π-π stacking Pyrrolo[1; 2-b]pyridazine; crystal structure; π-π stacking
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Caira, M.R.; Dumitrascu, F.; Draghici, C.; Dumitrescu, D.; Cristea, M. Synthesis and X-ray Structure of a New Pyrrolo[1,2-b]-pyridazine Derivative. Molecules 2005, 10, 360-366.

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