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New Route to 3-Alkylthiazolo[3,2-a]benzimidazole Derivatives
UMR “Chirotechnologies: Catalyse et Biocatalyse”, Université Paul Cézanne Aix-Marseille III, 13397 Marseille CEDEX 20 France
* Author to whom correspondence should be addressed.
Received: 29 October 2004 / Accepted: 16 December 2004 / Published: 28 February 2005
Abstract: 3-Alkyl-thiazolo[3,2-a]benzimidazole derivatives are obtained in high yieldsvia the corresponding 4-alkyl-N-3-(2-aminophenyl)-thiazoline-2-thiones which are easilyprepared from 1,2-diaminobenzene, CS2 and halogenoketones. This new route comparesadvantageously with the classical mercaptobenzimidazole routes in term of simplicity,isolated yields and availability of the starting materials.
Keywords: 2-Methylthiothiazolium salts; fused heterocycles; ring closure.
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MDPI and ACS Style
Roussel, C.; Andreoli, F.; Roman, M.; Hristova, M.; Vanthuyne, N. New Route to 3-Alkylthiazolo[3,2-a]benzimidazole Derivatives. Molecules 2005, 10, 327-333.
Roussel C, Andreoli F, Roman M, Hristova M, Vanthuyne N. New Route to 3-Alkylthiazolo[3,2-a]benzimidazole Derivatives. Molecules. 2005; 10(2):327-333.
Roussel, Christian; Andreoli, Federico; Roman, Mihaela; Hristova, Maria; Vanthuyne, Nicolas. 2005. "New Route to 3-Alkylthiazolo[3,2-a]benzimidazole Derivatives." Molecules 10, no. 2: 327-333.