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Molecules 2005, 10(2), 327-333; doi:10.3390/10020327

New Route to 3-Alkylthiazolo[3,2-a]benzimidazole Derivatives

UMR “Chirotechnologies: Catalyse et Biocatalyse”, Université Paul Cézanne Aix-Marseille III, 13397 Marseille CEDEX 20 France
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Received: 29 October 2004 / Accepted: 16 December 2004 / Published: 28 February 2005
(This article belongs to the Special Issue Sulfur-Nitrogen Heterocycles)
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Abstract

3-Alkyl-thiazolo[3,2-a]benzimidazole derivatives are obtained in high yieldsvia the corresponding 4-alkyl-N-3-(2-aminophenyl)-thiazoline-2-thiones which are easilyprepared from 1,2-diaminobenzene, CS2 and halogenoketones. This new route comparesadvantageously with the classical mercaptobenzimidazole routes in term of simplicity,isolated yields and availability of the starting materials.
Keywords: 2-Methylthiothiazolium salts; fused heterocycles; ring closure. 2-Methylthiothiazolium salts; fused heterocycles; ring closure.
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Roussel, C.; Andreoli, F.; Roman, M.; Hristova, M.; Vanthuyne, N. New Route to 3-Alkylthiazolo[3,2-a]benzimidazole Derivatives. Molecules 2005, 10, 327-333.

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