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Molecules 2005, 10(10), 1325-1334; doi:10.3390/10101325

Facile Preparation of Peracetates and Per-3-bromobenzoates of α-Mono- and Disaccharides

* ,  and
Department of Chemistry, School of Sciences and Computer Engineering, University of Houston-Clear Lake, 2700 Bay Area Boulevard, Houston, TX 77058, USA
* Author to whom correspondence should be addressed.
Received: 1 July 2005 / Revised: 12 July 2005 / Accepted: 12 July 2005 / Published: 31 October 2005
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A simple and convenient method for the preparation of fully acetylated and (3- bromo)benzoylated α-monosaccharides and disaccharides through vigorous mechanical mixing of solid reactants on a high speed shaker is described. Using this technique a variety of α-acylated sugars are prepared, including penta-O-acetyl-α-D-galactopyranose, penta-O- acetyl-α-D-glucopyranose, penta-O-acetyl-α-D-mannopyranose, octa-O-acetyl-α-lactose, penta-O-(3-bromo)benzoyl-α-D-galactopyranose, penta-O-(3-bromo)benzoyl-α-D-gluco- pyranose, penta-O-(3-bromo)benzoyl-α-D-mannopyranose, and octa-O-(3-bromo)benzoyl- α-lactose.
Keywords: α-Galactose; α-glucose; α-mannose; lactose; mechanochemical mixing α-Galactose; α-glucose; α-mannose; lactose; mechanochemical mixing
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Wang, Z.; Matin, M.; Sheikh, S. Facile Preparation of Peracetates and Per-3-bromobenzoates of α-Mono- and Disaccharides. Molecules 2005, 10, 1325-1334.

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