Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones
AbstractThree convenient methods of reduction of the nitro group of 5-nitroimidazoles and 5-nitrothiazole that bear a diethylmethylene malonate group in an ortho-like position with respect to the nitro group and cyclization of the resulting amino derivatives are reported. These reactions afforded the target bicyclic 2-pyridones in good to excellent yields.
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Crozet, M.D.; George, P.; Crozet, M.P.; Vanelle, P. Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones. Molecules 2005, 10, 1318-1324.
Crozet MD, George P, Crozet MP, Vanelle P. Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones. Molecules. 2005; 10(10):1318-1324.Chicago/Turabian Style
Crozet, Maxime D.; George, Pascal; Crozet, Michel P.; Vanelle, Patrice. 2005. "Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones." Molecules 10, no. 10: 1318-1324.