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Complexity through Recombination: From Chemistry to Biology
Department of Chemistry, Portland State University, P.O. Box 751, Portland, OR 97207, USA
Department of Biology and Biochemistry, University of Houston, 365 Science and Research Building 2, Houston, TX 77204, USA
Department of Biochemistry, University of Missouri, 117 Schweitzer Hall, Columbia, MO 65211, USA
* Author to whom correspondence should be addressed.
Received: 4 November 2010; in revised form: 14 December 2010 / Accepted: 20 December 2010 / Published: 24 December 2010
Abstract: Recombination is a common event in nature, with examples in physics, chemistry, and biology. This process is characterized by the spontaneous reorganization of structural units to form new entities. Upon reorganization, the complexity of the overall system can change. In particular the components of the system can now experience a new response to externally applied selection criteria, such that the evolutionary trajectory of the system is altered. In this work we explore the link between chemical and biological forms of recombination. We estimate how the net system complexity changes, through analysis of RNA-RNA recombination and by mathematical modeling. Our results underscore the importance of recombination in the origins of life on the Earth and its subsequent evolutionary divergence.
Keywords: recombination; transesterification; RNA; mutational robustness; genotypic landscape; naked genes
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MDPI and ACS Style
Lehman, N.; Arenas, C.D.; White, W.A.; Schmidt, F.J. Complexity through Recombination: From Chemistry to Biology. Entropy 2011, 13, 17-37.
Lehman N, Arenas CD, White WA, Schmidt FJ. Complexity through Recombination: From Chemistry to Biology. Entropy. 2011; 13(1):17-37.
Lehman, Niles; Arenas, Carolina Díaz; White, Wesley A.; Schmidt, Francis J. 2011. "Complexity through Recombination: From Chemistry to Biology." Entropy 13, no. 1: 17-37.