Reprint
Past, Present, and Future of Radiochemical Synthesis
Edited by
January 2024
184 pages
- ISBN978-3-03928-614-0 (Hardback)
- ISBN978-3-03928-613-3 (PDF)
This book is a reprint of the Special Issue Past, Present, and Future of Radiochemical Synthesis that was published in
Chemistry & Materials Science
Medicine & Pharmacology
Summary
The purpose of this Special Issue was to host research and review papers on the past, present, and future of radiochemical synthesis. The Special Issue contains nine original research papers and two reviews within the area of radiochemistry. These address how and why a certain radioactive compound has been prepared, how a radioactive compound has taken our understanding of a biological system to a different level, how a radiopharmaceutical can be used for treatment, and/or how a radioactive compound has improved our understanding of a certain drug (binding pattern and/or metabolization of the drug).
Format
- Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
fluorine-18; fluorination on Sep-Pak; [18F]FFNP; [18F]FDHT; mass spectrometry; molar activity; radiolabeling; bioorthogonal reaction; click chemistry; site-specific reaction; radiopharmaceuticals; radioisotopes; molecular imaging; fluorine-18; radiochemistry; late-stage radiofluorination; drug development; copper-catalyzed; boronic pinacol ester; Huntington’s disease; mutant huntingtin; Positron Emission Tomography; radiochemistry; fluorine-18; carbon-11; radiopharmaceuticals; [11C]raclopride; [18F]MNI-659; fluorine-18; peptide transporters; positron emission tomography; radiotracer; fluorination; ProTides; fluorine-18; radiolabelling; PET imaging; [18F]FPEB; mGluR5; positron emission tomography (PET); iodonium-ylide; Alzheimer’s Disease (AD); titanium-45; PSMA; PET; gastrin-releasing peptide receptor targeting; [99mTc]Tc-radiotracer; tumor targeting; [99mTc]Tc-DB1 mimic; PEGx-spacer; neprilysin-inhibition; phosphoramidon; radiolabeled somatostatin analogs; SST2; SST5; Lu-177; targeted radionuclide therapy; neuroendocrine tumors; dual-tumor mouse model; osteomyelitis; animal experimentation; pigs; PET/CT; [18F]FDG; [18F]NaF; [68Ga]Ga-DOTA-K-A9; [68Ga]Ga-DOTA-GSGK-A11 [68Ga]Ga-DOTA-Siglec-9; [68Ga]Ga-ubiquicidin