Targeting the Microbiome for Disease Diagnosis and Therapy: New Frontiers for Personalized Medicine

Edited by
November 2022
280 pages
  • ISBN978-3-0365-5612-3 (Hardback)
  • ISBN978-3-0365-5611-6 (PDF)

This book is a reprint of the Special Issue Targeting the Microbiome for Disease Diagnosis and Therapy: New Frontiers for Personalized Medicine that was published in

Medicine & Pharmacology
Public Health & Healthcare

Background: The gut microbiota is emerging as a pivotal player in the pathogenesis of many non-communicable diseases. Thus, it has been proposed as a new diagnostic and therapeutic target.Aim and scope: This Special Issue will focus on the microbiome as a potential target of new personalized therapies or diagnostic tools.History: In recent decades, the gut microbiome has been deeply investigated, and many studies have provided new information on the role of dysbiosis in many gastrointestinal and extra-gastrointestinal diseases. Recently, in addition to its phylogenetic characterization, new information has become available regarding the function of the gut microbiota, thanks to proteomic and metabolomic analyses.Cutting-edge research: The therapeutic modulation of the gut microbiota based on different strategies, including diet modification, antibiotics, prebiotics, probiotics, and, last but not least, fecal microbiota transplantation, has been tested for the treatment of various diseases. Recently, the possible applications and modalities of gut microbiota modulation have been increasingly expanding.We have collected original clinical or pre-clinical research papers and reviews focusing on the use of the microbiome for disease diagnosis, monitoring, or therapy and suggesting new possible gut microbiota-based approaches for personalized care.

  • Hardback
License and Copyright
© 2022 by the authors; CC BY-NC-ND license
Graves–Basedow’s diseases; Hashimoto’s thyroiditis; autoimmunity; gut microbiota; irritable bowel syndrome; microbiota; microbiome; food components; nutrients; hematopoietic stem cell transplantation; fecal microbiota transplantation; gut microbiota; aGvHD; antibiotic-resistant bacteria; cystic fibrosis; rabbits; intestinal dysbiosis; feces microbiome; microbiome; beta-blocker; hemodialysis; next-generation sequencing; propensity score matching methods; violin plots; random sampling; analytical reproducibility; microbiome; fecal matter transplantation; data disease subtypes; personalized medicine; maltodextrin; dip test; gallstone disease; 16S rDNA gene diversity; gut microbiota; blood biochemical characteristics; mesothelioma; microbiome; 16S RNA sequencing; species; gut microbiota; probiotics and gut disease; probiotics and acute diverticulitis; probiotics and diverticular disease; probiotics mechanism of action; IgA Nephropathy; rifaximin; microbiota; α1KI-CD89Tg mice; children; intermittent hypoxemia; microbiome; obstructive sleep apnea; tonsil; weight status; oral microbiota; microbiome; rheumatology diseases; biomarkers; artificial intelligence; machine learning; rheumatoid arthritis; Sjogren’s syndrome; systemic lupus erythematosus; endometrial cancer; endometrial microbiome; gut microbiome; dysbiosis; estrogen metabolism; estrobolome; inflammation; antitumour treatment; prebiotics; probiotics; gut microbiota; schizophrenia; depression; anxiety; probiotics; functional genes; thymoma; microbiome; 16S RNA sequencing; genera; driver mutation; cardiovascular diseases; 16S RNA sequencing; microbiome; biomarkers; critically ill; intestinal permeability; gut microbiome; recurrent cystitis; dysbiosis; n/a

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