Derivatization in Analytical Chemistry

Book cover
Edited by
May 2022
210 pages
  • ISBN978-3-0365-4256-0 (Hardback)
  • ISBN978-3-0365-4255-3 (PDF)

This book is a reprint of the Special Issue Derivatization in Analytical Chemistry that was published in

Chemistry & Materials Science
Medicine & Pharmacology

Derivatization is one of the most widely used sample pretreatment techniques in Analytical Chemistry and Chemical Analysis. Reagent-based or reagent-less schemes offer improved detectability of target compounds, modification of the chromatographic properties and/or the stabilization of sensitive compounds until analysis. Either coupled with separation techniques or as a “stand alone” analytical procedure, derivatization offers endless possibilities in all aspects of analytical applications.

  • Hardback
© by the authors
tyrosine kinase inhibitors; chloranilic acid; charge-transfer reaction; 96-microwell spectrophotometric assay; high-throughput pharmaceutical analysis; biogenic amines; Lycium barbarum L.; HPLC; derivatization; amino acids; derivatization; esterification; GC–MS; pentafluoropropionic anhydride; stability; toluene; GC–MS; pigment; linseed oil; derivatisation; quantification; P/S ratio; A/P ratio; ∑D; amino acids; derivatization; esterification; GC-MS; pentafluoropropionic anhydride; ureide; BSTFA; creatine; creatinine; derivatization; quantification; silylation; TMS; validation; low-molecular-weight thiols; human serum albumin; α-lipoic acid; blood plasma; derivatization; monobromobimane; reduction; sodium borohydride; high-performance liquid chromatography; fluorescence detection; taurine; glutamine; derivatization; clams; high-resolution mass spectrometry; nerve agents; GC-MS; derivatization; silylation; methylation; chemical warfare agents; sarin; Novichoks; 2-naphthalenethiol; derivatization; sulforaphane; HPLC-UV/Vis; pharmacokinetics; acetonitrile-related adducts; acetylenic lipids; double and triple bond localization; in-source derivatization; mass spectrometry; acetazolamide; carbonic anhydrase; derivatization; enhancement; GC-MS; inhibition; pentafluorobenzyl bromide; chiral metabolomics; rice water; d-amino acids; enantiomer separation; dimethyl labeling; homocysteine thiolactone; homocysteine; zone fluidics; o-phthalaldehyde; fluorosurfactant-modified gold nanoparticles