Intervertebral Disc Regeneration

Edited by
January 2022
138 pages
  • ISBN978-3-0365-2754-3 (Hardback)
  • ISBN978-3-0365-2755-0 (PDF)

This book is a reprint of the Special Issue Intervertebral Disc Regeneration that was published in

Biology & Life Sciences
Chemistry & Materials Science
Computer Science & Mathematics
Environmental & Earth Sciences
Physical Sciences

This book provides a brief snapshot of recent research on the subject of intervertebral disc degeneration and how this specific organ could be regenerated. It provides stimuli to the reader in representing research from different angles in this cross-disciplinary field of spine surgeons, mechanical engineers and biologists. In particular, it is instructive as to how disc herniations could be successfully induced in vitro and, also, to how novel cell-based therapies using rare autochthonous stem cells could potentially be used in the future.

  • Hardback
© 2022 by the authors; CC BY-NC-ND license
hyaluronic acid; disc repair; annulus fibrosus repair; biomaterials; inflammatory biomarkers and signalling pathways; nasal chondrocytes; disc degeneration; inflammation; microenvironment; nucleus pulposus; cell; spine; intervertebral disc; renin–angiotensin system; degeneration; regeneration; spine; inflammation; intervertebral disc (IVD); regeneration; stem cell; biomaterials; scaffolds; tissue engineering; test method; dynamic testing; in vitro; (lumbar) disc herniation; physiological activities; regenerative approaches; tissue engineering; intervertebral disc; nucleus pulposus; nucleus pulposus progenitor cells; cryopreservation; Tie2; spheroid colony; EZSPHERE; CryoStor 10; nucleus pulposus; growth factors; differentiation; mesenchymal stromal cell; growth factor; Wnt; differentiation factor; chondrogenesis; cell therapy; biomaterials; tissue engineering; progenitor cells; cell therapy; biomechanics; lumbar disc herniation; GDF5; GDF6; TGFβ; nucleus pulposus progenitor cells (NPPC); losartanon