Apheresis in Neurological Disorders

Edited by
December 2020
174 pages
  • ISBN978-3-03943-585-2 (Hardback)
  • ISBN978-3-03943-586-9 (PDF)

This book is a reprint of the Special Issue Apheresis in Neurological Disorders that was published in

Medicine & Pharmacology
Public Health & Healthcare
Apheresis refers to an extracorporeal therapy which aims at removing pathological constituents from the patients’ blood. Due to the development of new techniques as well as the discovery of novel autoimmune antibodies, it is increasingly recognized as an important therapeutic option for a variety of autoimmune-mediated neurological disorders, including multiple sclerosis, myasthenia gravis, autoimmune encephalitis, Guillain–Barré syndrome, and many others. Therapeutic plasma exchange (TPE) constitutes the standard method of apheresis for most indications, while immunoadsorption (IA) offers a more specific, low-risk alternative. Both methods aim at removing auto-antibodies from the blood. Evidence for most neurological diseases is still low. Interestingly, more recent developments suggest that apheresis is not limited to the removal of autoantibodies but may also be useful in neurodegenerative and possibly even in acute vascular disorders.
  • Hardback
License and Copyright
© 2021 by the authors; CC BY-NC-ND license
immunoadsorption; acute relapsing multiple sclerosis; plasma exchange; therapeutic apheresis; multiple sclerosis; optic neuritis; plasma exchange; relapse; class IV; steroids; multiple sclerosis; plasma exchange; immunoadsorption; Alzheimer’s clinical syndrome; dementia; immunoadsorption; autoantibodies; α1-Adrenergic receptor; Inflammatory neuropathy; chronic inflammatory demyelinating polyneuropathy; Guillain-Barré syndrome; multiple sclerosis; paranodal antibodies; plasmapheresis; plasma exchange; immunoadsorption; Myalgic Encephalomyelitis/Chronic Fatigue Syndrome; immunoadsorption; ß2 adrenoreceptor autoantibody; autoimmune encephalitis; limbic encephalitis; NMDAR (N-Methyl-D-Aspartat); antibody; paraneoplastic; apheresis; plasma exchange; immunoadsorption; therapeutic plasma exchange; immunoadsorption; neurological diseases; multiple sclerosis; chronic inflammatory demyelinating polyneuropathy; CRP; apheresis; stroke; inflammation; n/a