Advances in Celiac Disease

Edited by
November 2020
128 pages
  • ISBN978-3-03943-384-1 (Hardback)
  • ISBN978-3-03943-385-8 (PDF)

This book is a reprint of the Special Issue Advances in Celiac Disease that was published in

Biology & Life Sciences
Medicine & Pharmacology
Public Health & Healthcare
The incidence of gluten-related disorders (GRDs) continues to increase and its global prevalence is estimated affect to 5% of the population. s. Celiac disease (CD), Dermatitis Herpetiformis (DH), Gluten Ataxia (GA), wheat allergy (WA), and Non-Celiac Gluten Sensitivity (NCGS) are the five major GRDs that present with a wide range of clinical manifestations. They are manifested by symptoms of gastrointestinal tract disorders, as well as hematological, dermatological endocrinological, gynecological, rheumatological and nervous system. NCGS is a term that is used to describe individuals who are not affected by celiac disease or wheat allergy, yet they have intestinal and/or extra-intestinal symptoms related to gluten ingestion with improvement of their symptoms upon withdrawing gluten from their diet. It is believed that represents some heterogeneous groups with different subgroups characterized by different etiologies, clinical histories and clinical courses. There also appears to be an overlap between NCGS and irritable bowel syndrome (IBS). There is a need for establishing strict criteria for diagnosing NCGS. The absence of validated biomarkers remains a significant limitation for research studies on NCGS. New evidence shows that a gluten-free diet may be beneficial for some patients with gastrointestinal symptoms, such as those symptoms commonly found in patients with IBS.
  • Hardback
License and Copyright
© 2021 by the authors; CC BY license
celiac disease; children; HLA-DQ; prevalence; Asia; celiac disease; wheat; gluten; non-celiac gluten-sensitivity; diagnosis; dermatitis herpetiformis; anti-tTG; anti-DGP; AAA; AGA; IL-17A; celiac disease; children; HLA-DQB1*02; screening; first-degree relatives; non-celiac gluten sensitivity; irritable bowel disease; gluten; FODMAP; wheat allergy; celiac disease; vitamin B12; iron; folic acid; vitamin D; long-term GFD therapy (LTGFD); LTGFD with good compliance (LTGFDWGC); celiac disease; anemia; lymphoma; IgA deficiency; gluten; gut; enteropathy; gluten-free diet; level of evidences; celiac disease; gluten-free diet; gluten-related disorders; NCGS; self-report; survey studies; n/a

Related Books

September 2022

Gluten Related Disorders: Coeliac Disease and Beyond

Biology & Life Sciences
January 2021

Advance in Gluten-Free Diet

Public Health & Healthcare
April 2019

Gluten-Free Diet

Public Health & Healthcare
April 2019

Extraintestinal Manifestations of Coeliac Disease

Public Health & Healthcare