Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials

Edited by
August 2019
186 pages
  • ISBN978-3-03921-259-0 (Paperback)
  • ISBN978-3-03921-260-6 (PDF)

This book is a reprint of the Special Issue Nucleic Acid Architectures for Therapeutics, Diagnostics, Devices and Materials that was published in

Chemistry & Materials Science

Nucleic acids (RNA and DNA) and their chemical analogs have been utilized as building materials due to their biocompatibility and programmability. RNA, which naturally possesses a wide range of different functions, is now being widely investigated for its role as a responsive biomaterial which dynamically reacts to changes in the surrounding environment. It is now evident that artificially designed self-assembling RNAs, that can form programmable nanoparticles and supra-assemblies, will play an increasingly important part in a diverse range of applications, such as macromolecular therapies, drug delivery systems, biosensing, tissue engineering, programmable scaffolds for material organization, logic gates, and soft actuators, to name but a few. The current exciting Special Issue comprises research highlights, short communications, research articles, and reviews that all bring together the leading scientists who are exploring a wide range of the fundamental properties of RNA and DNA nanoassemblies suitable for biomedical applications.

  • Paperback
© 2019 by the authors; CC BY-NC-ND license
logic gates; nucleic acid computing; RNA aptamers; RNA nanotechnology; glioblastoma multiforme; gene therapy; viral vector; non-viral vector; gene delivery; siRNA; RNA aptamers; biosensors; live-cell imaging; fluorogenic RNA; riboswitch; ribozyme; RNA nanotechnology; RNA self-assembly; light-up aptamer; RNA nanoparticle; DNA nanotechnology; nanopores; biological media; serum; stability; aggregation; RNA nanotechnology; aptamers; cotranscriptional folding; suicide gene therapy; non-viral gene delivery; ganciclovir; spinal cord tumor; nucleic acid nanoparticles; NANPs; immunostimulation; dynamic; conditionally activated; RNA interference; RNA nanotechnology; silver nanoclusters; fluorescence; i-motif DNA; cytosine rich sequences; RNA; RNA logic; conditional activation; functional RNA; nucleic acid therapeutic; small-angle X-ray scattering; small-angle neutron scattering; contrast variation; nucleic acid nanoparticle; structural characterization; n/a