Discovery of Bioactive Compounds from Natural Organisms and Their Molecular Mechanisms against Diseases

Discovering bioactive compounds and their molecular mechanisms of disease resistance from natural organisms is an important frontier in current drug development, agricultural biological control, and life science research. This research not only provides new solutions for the treatment of human diseases and the prevention and control of animal and plant diseases and pests, but it also provides key clues for understanding the molecular mechanisms of life activities. However, the research and development of synthetic drugs is currently facing increasingly severe challenges, which are manifested in rising research and development costs, longer cycles, a sharp decline in success rates, and increasingly serious environmental pollution problems. Therefore, finding lead compounds to develop new drugs has become a core priority for major pharmaceutical companies. During the long evolutionary process, organisms have synthesized a large number of secondary metabolites with novel and unique structures. The differences in the chemical properties of these organisms not only give them diverse biological activities but also provide the possibility of exploring new mechanisms of action. Therefore, they have become an indispensable resource in the development of new drugs—people are working to discover new lead compounds from millions of plants, animals, microorganisms, and marine organisms in nature. This reprint is highly recommended for researchers, students, and industry professionals because it provides new insights into “bioactive compounds and their molecular mechanisms of disease resistance”.