Diagnosis and Surgical Treatment of Epilepsy

Edited by
December 2018
134 pages
  • ISBN978-3-03897-449-9 (Paperback)
  • ISBN978-3-03897-450-5 (PDF)

This book is a reprint of the Special Issue Diagnosis and Surgical Treatment of Epilepsy that was published in

Biology & Life Sciences
Computer Science & Mathematics
Medicine & Pharmacology
Public Health & Healthcare

Epilepsy is a common neurological disease that can affect all ages. Although the majority of people with epilepsy can have excellent seizure control with medication, about 30% will fail anti-epileptic drugs. For those with medically intractable epilepsy, recurrent seizures lead to elevated mortality and injury risks, and the seizures themselves are socially disabling. Fortunately, for many people with intractable epilepsy, epilepsy can be cured or seizures better controlled with surgery.


Localization of the seizure focus followed by surgical resection provide the best opportunities to cure epilepsy. Having a better understanding of the neuro-anatomy and physiology of epilepsy improves our ability to define the epileptic network and effectively treat epilepsy. Minimal access surgical approaches result in more rapid recovery from surgery, less pain, and more satisfied patients.


For individuals without an opportunity to cure their epilepsy, new and emerging technologies can improve their quality of life by preventing injuries and reducing seizure frequency and severity.


This Special Issue will highlight advances in the diagnosis and surgical treatment of epilepsy, including imaging and electroencephalography (EEG) approaches to defining the epileptic focus, understanding the epileptic network, and characterizing the anatomical substrate of epilepsy.

  • Paperback
© 2019 by the authors; CC BY-NC-ND license
brain stimulation; neuromodulation; epilepsy; surgery; epilepsy; epilepsy surgery; decision analysis; treatment gap; game theory; economics; efficiency; resource allocation; return on investment; temporal lobe epilepsy; selective amygdalohippocampectomy; epilepsy surgery; mesial temporal lobe epilepsy; temporal lobe epilepsy; encephalocele; meningoencephalocele; tailored surgery; l-carnitine; PTZ; epilepsy; apoptosis; β-catenin; oxidative stress; medically intractable epilepsy; EEG; epilepsy surgery; MRI; epilepsy; seizures; medically intractable epilepsy; surgery of epilepsy; stigma; quality of life; developing world; epilepsy; neuromodulation; randomized clinical trials (RCT); deep brain stimulation (DBS); transcranial direct current stimulation (tDCS); vagal nerve stimulation (VNS); external trigeminal nerve stimulation (eTNS); repetitive transcranial magnetic stimulation (rTMS); responsive neurostimulation (RNS); n/a; intracranial monitoring; subdural electrodes; intracranial electrodes; seizure focus localization; chronic monitoring; epilepsy surgery; seizure monitoring; seizure prediction