Reprint
Micro- and Macro-Environmental Factors in Solid Cancers
Edited by
April 2021
120 pages
- ISBN978-3-0365-0692-0 (Hardback)
- ISBN978-3-0365-0693-7 (PDF)
This book is a reprint of the Special Issue Micro- and Macro-Environmental Factors in Solid Cancers that was published in
Biology & Life Sciences
Medicine & Pharmacology
Summary
Although cancer development and progression depend on stochastic mutational events, the tumor has to be seen in the context of the host environment, and unraveling the environmental factors that support solid tumors is at the root of cancer prevention and cure. This Special Issue, focused on the dynamic crosstalk that occurs between tumor cells and the surrounding microenvironment and also including the cancer cells that represent a reservoir of self-sustaining cells for tumor maintenance, adds new knowledge about tumor–host interactions that is useful for novel diagnostic and therapeutic approaches.
Format
- Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
esophageal carcinogenesis; extracellular matrix; stiffness; remodeling; adhesion; metalloproteinases; glycoproteins; proteoglycans; cancer stem cells; immunotherapy; tumor microenvironment; immune checkpoint blockade; adipocytes; breast cancer; obesity; adipokines; cancer associated adipocytes (CAAs); cachexia; prostaglandin-endoperoxide synthase-2/Cyclooxygenase 2 (PTGS2/COX-2); colorectal cancer (CRC); non-steroidal anti-inflammatory drugs (NSAIDS); cancer-associated fibroblasts (CAF); interleukin-1 beta (IL1β); macrophages; PDAC; tumor microenvironment; CCN2/CCN3; matricellular proteins; tumor microenvironment; triple-negative breast cancer; cancer-associated fibroblasts; EFEMP1; miRNA; miR-9; chemoresistance; n/a