Reprint
Comorbidities in Chronic Kidney Disease (CKD)
Edited by
March 2021
184 pages
- ISBN978-3-03936-668-2 (Hardback)
- ISBN978-3-03936-669-9 (PDF)
This book is a reprint of the Special Issue Comorbidities in Chronic Kidney Disease (CKD) that was published in
Biology & Life Sciences
Medicine & Pharmacology
Public Health & Healthcare
Summary
With a mean worldwide prevalence of 13%, chronic kidney disease imposes a massive health burden on our society. In addition to reduced kidney function, patients with chronic kidney disease increasingly suffer from cardiovascular diseases affecting the heart and vasculature. Cardiovascular diseases account for around half of the deaths of patients with advanced chronic kidney disease. However, therapeutic options are highly insufficient. The pathological mechanisms that underlie increased cardiovascular risk in patients with chronic kidney disease remain largely unknown. This Special Issue provides insights into comorbidities in CKD patients, mainly focused on increased cardiovascular risk, and summarizes current knowledge of underlying pathophysiological mechanisms.
Format
- Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
arterial stiffness; carotid–femoral pulse wave velocity; hemodialysis; p-cresyl sulfate; uremic toxins; arterial calcification; lipid metabolism; inflammation; coagulation; endothelial dysfunction; epigenetics; chronic kidney disease; uremic cardiopathy; left ventricular hypertrophy; phosphate; PTH; FGF23; klotho; sclerostin; chronodisruption; chronodisruptor; circadian rhythm; internal clock; chronic kidney disease; uremia; uremic cardiomyopathy; organ crosstalk; cardiorenal syndrome; chronic kidney disease; left-ventricular hypertrophy; heart failure; cardiac fibrosis; chronic kidney disease; cardiovascular disease; vascular calcification; experimental rodent models; FGFG23; Klotho; Wnt/β-catenin; CKD; cardiorenal syndrome; parathyroid hormone; secondary hyperparathyroidism; uremic toxin; ageing; chronic kidney disease; end-stage kidney disease; inflammation; premature ageing; senescence; uremic toxins; bone; vascular calcification; gut; CKD; chronic kidney disease; cardiovascular; CKD–MBD; comorbidity; inflammation; fibrosis; calcification; senescence; uremic toxin