Reprint
Bioprocess Monitoring and Control
Edited by
September 2020
234 pages
- ISBN978-3-03936-932-4 (Hardback)
- ISBN978-3-03936-933-1 (PDF)
This book is a reprint of the Special Issue Bioprocess Monitoring and Control that was published in
Biology & Life Sciences
Chemistry & Materials Science
Computer Science & Mathematics
Engineering
Environmental & Earth Sciences
Summary
Process monitoring and control are fundamental to all processes; this holds especially for bioprocesses, due to their complex nature. Usually, bioprocesses deal with living cells, which have their own regulatory systems. It helps to adjust the cell to its environmental condition. This must not be the optimal condition that the cell needs to produce whatever is desired. Therefore, a close monitoring of the cell and its environment is essential to provide optimal conditions for production. Without measurement, no information of the current process state is obtained. In this book, methods and techniques are provided for the monitoring and control of bioprocesses. From new developments for sensors, the application of spectroscopy and modelling approaches, the estimation and observer implementation for ethanol production and the development and scale-up of various bioprocesses and their closed loop control information are presented. The processes discussed here are very diverse. The major applications are cultivation processes, where microorganisms were grown, but also an incubation process of bird’s eggs, as well as an indoor climate control for humans, will be discussed. Altogether, in 12 chapters, nine original research papers and three reviews are presented.
Format
- Hardback
License
© 2020 by the authors; CC BY-NC-ND license
Keywords
bioenvironmental control; model-predictive controller; zonal controlling; dynamic modelling; flotation; bioleaching; frother; mixed culture; machine learning; Raman spectroscopy; downstream processing; chromatography; flow cell; extended Kalman filter; biotechnological processes; bioreactor control; specific growth rate control; batch-to-batch reproducibility; thermal sensation; thermal comfort; machine-learning; prediction; adaptive controlling; thermal growth curve; temperature modeling; thermoregulation; monitoring and control; bioprocess engineering; calorimetry; biocontrol agent; Bacillus subtilis natto; isolation; molecular identification; medium optimization; antimicrobial activity; bactericides; spectral analyses; biological selenate reduction; electron donor competition; nitrate; perchlorate; sequencing batch; Pseudomonas; siderophores; antagonism; batch fermentation; exponential fed-batch fermentation; bio-friendly formulations; biocontrol; nonlinear state estimation; geometric observer; bioreactor; continuous system; extended Kalman filter; model-based sensor; well-defined macromolecules; sequence-defined macromolecules; sequence-defined polymers; conjugated oligomers; oligo(arylene ethynylene)s; biosensors; sensors; process monitoring; bioprocess monitoring and control; specific growth rate control; signal noise management; dielectric spectroscopy; PAT; microbial bioprocessing; n/a