Reprint
Emerging Role of Lipids in Metabolism and Disease
Edited by
April 2021
308 pages
- ISBN978-3-03943-701-6 (Hardback)
- ISBN978-3-03943-702-3 (PDF)
This book is a reprint of the Special Issue Emerging Role of Lipids in Metabolism and Disease that was published in
Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary
Even though initially considered as a passive means for storing energy, lipids are now regarded as multifaceted molecules with crucial structural and functional activities. For instance, some of them play essential roles as key components of cell membranes whereas others act as signaling molecules in the regulation of cell homeostasis. In recent years, lipid research has attracted increasing interest because of the involvement of this class of compounds in human health. Indeed, a plethora of pathological conditions are characterized by alterations in lipid metabolism, such as cardiovascular diseases and brain disorders. This Special Issue is a collection of papers from different experts in lipid research, with the aim of providing new insights into the physiopathological involvement of lipids and their impact on human health. This collection also demonstrates the usefulness of interdisciplinary approaches in the development of novel methods to study and manipulate lipid metabolism, which may represent an attractive target for designing effective therapeutic strategies to counteract numerous pathologies.
Format
- Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
neutral sphingomyelinase; radiation; sphingomyelin metabolism; pathology; cell signaling; brain; adipose tissue; breast cancer; epinephrine; breast reconstruction; epicardial fat thickness; visceral fat thickness; high-sensitivity c-reactive protein; leptin; gender; female; adipose tissue; hippocampus; frontal cortex; adiponectin; haptoglobin; lipocalin; BDNF; synaptic proteins; phosphatidylinositol 4,5-bisphosphate; phospholipase C; cholesterol; high-cholesterol diet; BET proteins; cell proliferation; cholesterol; epigenetics; HMGCR; JQ1; LDLr; lipid metabolism; SREBP; TMEM97; atherosclerosis; diabetes mellitus; cardiovascular disease; chronic inflammation; lipid metabolism; hyperglycemia; atherosclerosis; mutations; epigenetics; lipid; fatty acid; glyceride; steroid; phospholipid; oral drug absorption; prodrug; phospholipase A2 (PLA2); acid sphingomyelinase; neutral sphingomyelinase; radiation; SOD; liver; eicosanoids; cholesterol; ischemic stroke; ischemia; lipoproteins; polyunsaturated fatty acids; diabetes mellitus; angiogenesis; high-density lipoprotein; endothelial cell; metabolism; metabolic reprogramming; pulmonary fibrosis; lipid mediators; sphingolipids; sphingosine-1-phosphate; sphingosine kinase 1; prostaglandins; lysophosphatidic acid; autotaxin; G-protein coupled receptors; lysocardiolipin acyltransferase; phospholipase D; oxidized phospholipids; DNA damage response; double strand breaks; ATM; ionizing radiation; metabolic stress; oxidative stress; p53; sphingolipids; nuclear sphingolipids; lipophagy; lipolysis; lipid metabolism; lipid droplets; lipid storage diseases; lipid metabolism diseases; mTORC1; TFEB; Cholesterol; Fatty acids; Lipid mediators; Lipids; Lipophagy; Sphingolipids