Open Access Book

Advances in Aquatic Invertebrate Stem Cell Research

From Basic Research to Innovative Applications

Edited by
February 2022
398 pages
  • ISBN978-3-0365-1636-3 (Hardback)
  • ISBN978-3-0365-1635-6 (PDF)
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Biology & Life Sciences

Aquatic invertebrates represent the largest biodiversity and the widest phylogenetic radiation on Earth, with more than 2 million known species. Up until a few years ago, their use as Model organisms in biological research was limited by the paucity of omics data. Recently, the situation has rapidly changed and is still changing. Today, the genomes and various transcriptomes of many aquatic invertebrate species, as well as many recombinant proteins of invertebrate origin, are available. New technologies have revolutionised the available toolbox of research methodologies. This explains the rising interest of researchers in the use of aquatic invertebrates as reliable model organisms. In contrast to the prevalence of diverse oligopotent and unipotent stem cells in vertebrates, aquatic invertebrates (especially non-ecdysozoan invertebrates) exhibit multiple adult cell types with stem cell attributes characterised by multipotency and pluripotency; furthermore, these give rise to cell lineages characteristic of more than a single germ layer, sometimes with somatic and germ line potentials. In addition, unlike vertebrates, aquatic invertebrate adult stem cells are disseminated and widespread inside the animal body, are not associated with a regulatory microenvironment (niche), and do participate in ageing and regeneration phenomena. These properties can help us to better understand the processes and phenomena in mammalian stem cell biology, such as natural chimerism and cancer, ageing and senescence, immunity, and autoimmune responses, which are all difficult to explain or understand in the human context.

  • Hardback
© 2022 by the authors; CC BY-NC-ND license
aquaculture; fisheries; stem cell
This research and publication were funded by European Cooperation in Science & Technology (COST).
Review mode

Each chapter in this edited book has been reviewed by the editor/s, and a minimum of two external single-blind reviewers. The opinions expressed in the chapters do not reflect the view of the publisher.

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