Reprint
Versatility of Glutathione Transferase Proteins
Edited by
March 2024
164 pages
- ISBN978-3-7258-0453-5 (Hardback)
- ISBN978-3-7258-0454-2 (PDF)
This book is a reprint of the Special Issue Versatility of Glutathione Transferase Proteins that was published in
Biology & Life Sciences
Medicine & Pharmacology
Summary
Glutathione transferases are abundant enzymes in various aerobic organisms in which they provide cellular protection against reactive compounds that cause mutations and cancer. Their evolution may have been a response to oxidative stress caused by oxygen in the atmosphere. These enzymes also participate in steroid hormone synthesis in both mammals and insects and play important roles in the biotransformation of signaling substances. Their multiple roles also include the binding and transportation of molecules in cells.
Format
- Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
glutathione-S-transferase; nitroglycerin; nitric oxide; vasodilation; glutathione transferase; glutathione; cyanobacteria; Synechocystis sp. PCC 6803; crystallography; biochemistry; phylogeny; insects; glutathione transferase; olfaction; taste; chemosensory organs; detoxification; evolution; flavor; enzyme detoxication; substrate promiscuity; hydroxynonenal; lipid peroxidation; lipid alkenals; enzyme mechanism; deuterium exchange; glutathione S-transferases (GSTs); insecticide; insect growth regulator (IGR); mosquito; ecdysone; ecdysteroid; Drosophila melanogaster; Aedes aegypti; steroid; flavonoid; anticancer drugs; cancer; human glutathione transferase P1-1 (hGSTP1-1); glutathione transferase; enzyme inhibition; multidrug resistance; pesticide; Glutathione S-transferases (GSTs); antioxidants; cancer-cell signaling; cell survival; chemoresistance; xenobiotic compounds; metabolism; GST inhibitors; glutathionylation; oxidative stress; JNK; apoptosis; GST Polymorphism; SARS-CoV-2; COVID-19; Nobo; Anopheles gambiae GSTE8; malaria; ketosteroids; ecdysteroidogenesis; glutathione transferase; intracellular chloride channel; metaxin; failed axon connections homolog; ganglioside-induced differentiation-associated protein; glutathione S-transferase C-terminal domain-containing protein; multi-tRNA synthetase complex; eukaryotic elongation factor 1; structure prediction; estrogen; glutathione transferase A3-3 (GST A3-3); steroidogenesis; testes; testosterone; progesterone; n/a