Reprint

Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases

Edited by
January 2024
186 pages
  • ISBN978-3-0365-9701-0 (Hardback)
  • ISBN978-3-0365-9700-3 (PDF)

This book is a reprint of the Special Issue Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases that was published in

Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary

This Special Issue, titled "Advances in Structure, Function and Molecular Targeting of DNA Topoisomerases", includes reports on new findings and topics of current interest in the topoisomerase field. Topics include structural, biochemical, and pharmacological studies and reviews for both eukaryotic and prokaryotic topoisomerases.

Format
  • Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
zoliflodacin; quinolones; DNA gyrase; topoisomerase IV; ESKAPE; antibiotic; spiropyrimidinetrione; NBTI; gepotidacin; structure; mini; topoisomerase II; catalytic inhibitors; poisons; DNA; salicylate; cardiotoxicity; MD simulation; quinolone; quinolone resistance; water–metal ion bridge; gyrase; topoisomerase; DNA topoisomerase; DNA supercoiling; DNA relaxation; DNA decatenation; type IA topoisomerase; type IIA topoisomerase; structural biology; DNA supercoiling; DNA topoisomerase I; DNA gyrase; supercoiling regulation; supercoiling homeostasis; nucleoid-associated proteins; topsoisomerase regulator; StaR; Z-DNA; topoisomerase IIα; topoII; GTP; bioinformatics; DNA topoisomerase; DNA topology; supercoil handedness; type II topoisomerase; DNA relaxation; DNA cleavage; thiosemicarbazone; topoisomerase; antitumor; bis-thiosemicarbazone; novel bacterial topoisomerase inhibitor; NBTI; type II topoisomerase; gyrase; topoisomerase IV; DNA cleavage; Neisseria gonorrhoeae; n/a; topoisomerase; DNA supercoiling; DNA topology; anticancer; DNA damage; transcription; chromatin; TOP2; TOP2B