Reprint
Anticancer Drugs Activity and Underlying Mechanisms
Edited by
October 2021
170 pages
- ISBN978-3-0365-2119-0 (Hardback)
- ISBN978-3-0365-2120-6 (PDF)
This book is a reprint of the Special Issue Anticancer Drugs Activity and Underlying Mechanisms that was published in
Biology & Life Sciences
Chemistry & Materials Science
Computer Science & Mathematics
Engineering
Environmental & Earth Sciences
Physical Sciences
Summary
Cancer is a multifactorial and very complex disease representing the second leading cause of death worldwide. Prevention, early diagnosis and the old and new arsenal of chemotherapics are useful tools in the fight against this disease. This Special Issue collects the last researches and literature reviews in the field of Medicinal Chemistry and Cancer Research, with particular regard to the metal complexes and drug repurposing and with a glance at the drug formulation and biological targets discovered through the combined use of in silico and in vitro studies.
Format
- Hardback
License
© 2022 by the authors; CC BY-NC-ND license
Keywords
ferrocenes; chemotherapy; cytotoxic effect; radiotherapy; radiosensitization; irradiation; cell death; molecular docking; in vitro; metastatic breast cancer; drug discovery; apoptosis; caspase 3; Lewis lung carcinoma; malloapelta B; nanoliposome; ibrutinib; Bruton’s tyrosine kinase; Btk; kinase inhibitor; ovarian cancer; gynecological oncology; solid tumors; CA-125; inhibitor of apoptosis proteins (IAPs); Smac/DIABLO; LCL161; birinapant; GDC-0152; diarylureas; antitumor agents; bis-aryl ureas; hepatocellular carcinoma (HCC); renal cell carcinoma (RCC); gastrointestinal stromal tumors (GISTs); metastatic colorectal cancer (mCRC); B-cell lymphomas; Schiff bases; antitumor agents; apoptosis; antiproliferative activity; imines; gold derivatives; cancer treatment; breast cancer; cytotoxicity; antitumor activity; NHC-gold complexes; actin; anticancer; anticancer; apoptosis; drugs repositioning; molecular docking studies; thalidomide analogs; tubulin; n/a