Reprint
Kidney Inflammation, Injury and Regeneration
Edited by
April 2020
496 pages
- ISBN978-3-03928-538-9 (Paperback)
- ISBN978-3-03928-539-6 (PDF)
This book is a reprint of the Special Issue Kidney Inflammation, Injury and Regeneration that was published in
Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary
Acute kidney injury (AKI) is still associated with high morbidity and mortality incidence rates, and also bears an elevated risk of subsequent chronic kidney disease. Although the kidney has a remarkable capacity for regeneration after injury and may recover completely depending on the type of renal lesions, the options for clinical intervention are restricted to fluid management and extracorporeal kidney support. The development of novel therapies to prevent AKI, to improve renal regeneration capacity after AKI, and to preserve renal function is urgently needed. The Special Issue covers research articles that investigated the molecular mechanisms of inflammation and injury during different renal pathologies, renal regeneration, diagnostics using new biomarkers, and the effects of different stimuli like medication or bacterial components on isolated renal cells or in vivo models. The Special Issue contains important reviews that consider the current knowledge of cell death and regeneration, inflammation, and the molecular mechanisms of kidney diseases. In addition, the potential of cell-based therapy approaches that use mesenchymal stromal/stem cells or their derivates is summarized. This edition is complemented by reviews that deal with the current data situation on other specific topics like diabetes and diabetic nephropathy or new therapeutic targets.
Format
- Paperback
License
© 2020 by the authors; CC BY-NC-ND license
Keywords
kidney injury; alport syndrome; modifier gene; nephrin; podocin; glomerular basement membrane; slit diaphragm; focal segmental glomerulosclerosis; inflammatory bowel disease (IBD); DSS-colitis; glomerular filtration barrier (GFB); type IV collagen; type I collagen; type V collagen; genotype; IL-18; polymorphism; renal cell carcinoma; Taiwan; mesenchymal stem cells; acute and chronic kidney disease; exosome; natural products; non-coding RNAs; microRNAs; long non-coding RNAs; renal fibrosis; biomarkers; therapeutics targets; rhabdomyolysis; pigment nephropathy; haem; NLRP3 inflammasome; acute kidney injury; hypertension; kidney; molecular signaling; hematuria; inflammation; oxidative stress; tubular injury; AKI; chronic kidney disease (CKD); mesenchymal stromal cells; extracellular vesicles; acute kidney injury; modified-MSCs; microRNA; mesenchymal stem cell; mesodermal stem cell; renal ischemia-reperfusion; inflammation; kidney transplantation; microRNA; extracellular vesicles; exosomes; B-cell attracting chemokine; CXCL13; kidney transplantation; allograft rejection; T cell-mediated rejection; diabetic nephropathy; lysophosphatidic acid; lysophosphatidic acid receptor; chronic kidney injury; kidney proximal tubule; acute kidney failure; signal transduction; transcription; CREB Regulated Transcriptional Coactivators (CRTC); cAMP Regulatory Element Binding Protein (CREB); Salt Inducible Kinase (SIK); Class IIa Histone Deacetylases (HDAC); lncRNA; long non-coding RNA; miRNA; kidney; glomerulus; podocyte; acute kidney injury; AKI; diabetic nephropathy; diabetic kidney disease; diabetic nephropathy; inflammation; signaling cascade; ischemia-reperfusion; acute kidney injury; stem cell; conditioned medium; inflammation; apoptosis; necrosis; regulated necrosis; kidney injury; tubular injury; glomerular injury; polyunsaturated fatty acids; omega-3 fatty acid; inflammatory maker; C-reactive protein; interleukin-6; LPS-binding protein; fibrosis; pericyte; myofibroblast; endotoxemia-induced oliguric kidney injury; arachidonic acid; cyclooxygenase; lipoxygenase; cytochrome P450; kidney inflammation; therapeutic target; obese kidney fibrosis; endotoxemia; ROS; cPLA2 and COX-2; IgA nephropathy; KIT assay; KIT-IgA score; noninvasive; diagnostics; prediction; diabetic kidney diseases; xanthine oxidase; glomerular damage; acute kidney injury; chronic kidney disease; renal progenitors; polyploidization; diabetic nephropathy; diabetes mellitus; GLP-1 receptor agonists; SGLT2 inhibitors; molecular mechanisms; chemerin; CmklR1; 2-kidney-1-clip; 2k1c; Thy1.1 nephritis; renovascular hypertension; renal inflammation; renal injury; renal fibrosis; inflammation; ischemia/reperfusion injury; Farnesiferol B; Nuclear Factor kappa-light-chain-enhancer of activated B cells (NF-κB); G-protein-coupled bile acid receptor (TGR5); renal stem cells; differentiation; scattered tubular cells; papilla; niches; renal tubular cells; epithelial cells; proximal tubule; cytotoxicity; injury; inflammation; empagliflozin; dapagliflozin; kidney; n/a