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Authors = Ian Clausen

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11 pages, 1297 KB  
Case Report
Use of Molecular Imaging Markers of Glycolysis, Hypoxia and Proliferation (18F-FDG, 64Cu-ATSM and 18F-FLT) in a Dog with Fibrosarcoma: The Importance of Individualized Treatment Planning and Monitoring
by Kamilla Westarp Zornhagen, Malene M. Clausen, Anders E. Hansen, Ian Law, Fintan J. McEvoy, Svend A. Engelholm, Andreas Kjær and Annemarie T. Kristensen
Diagnostics 2015, 5(3), 372-382; https://doi.org/10.3390/diagnostics5030372 - 11 Sep 2015
Cited by 3 | Viewed by 7982
Abstract
Glycolysis, hypoxia, and proliferation are important factors in the tumor microenvironment contributing to treatment-resistant aggressiveness. Imaging these factors using combined functional positron emission tomography and computed tomography can potentially guide diagnosis and management of cancer patients. A dog with fibrosarcoma was imaged using [...] Read more.
Glycolysis, hypoxia, and proliferation are important factors in the tumor microenvironment contributing to treatment-resistant aggressiveness. Imaging these factors using combined functional positron emission tomography and computed tomography can potentially guide diagnosis and management of cancer patients. A dog with fibrosarcoma was imaged using 18F-FDG, 64Cu-ATSM, and 18F-FLT before, during, and after 10 fractions of 4.5 Gy radiotherapy. Uptake of all tracers decreased during treatment. Fluctuations in 18F-FDG and 18F-FLT PET uptakes and a heterogeneous spatial distribution of the three tracers were seen. Tracer distributions partially overlapped. It appears that each tracer provides distinct information about tumor heterogeneity and treatment response. Full article
(This article belongs to the Collection Feature Papers)
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13 pages, 172 KB  
Conference Report
Seeking the Place of Conscience in Higher Education: An Augustinian View
by Ian Clausen
Religions 2015, 6(2), 286-298; https://doi.org/10.3390/rel6020286 - 24 Mar 2015
Cited by 2 | Viewed by 5830
Abstract
This article explores the place of conscience in higher education. It begins by reconstructing the place of conscience in Augustine’s thought, drawing on Augustine’s reading of Genesis 3, the Psalms, and his own spiritual journey. Its basic aim is to clarify Augustine’s account [...] Read more.
This article explores the place of conscience in higher education. It begins by reconstructing the place of conscience in Augustine’s thought, drawing on Augustine’s reading of Genesis 3, the Psalms, and his own spiritual journey. Its basic aim is to clarify Augustine’s account of conscience as self-judgment, identifying the conditions under which self-judgment occurs. After identifying these conditions it addresses the question: does conscience still have a place in modern higher education? It acknowledges the real limitations and obstacles to moral education when pursued in the context of the modern research university. However, it also argues that moral education proceeds in stages, and that educators can anticipate and clear a way for the place of conscience—though not, of course, without reliance on the movement of grace. Full article
(This article belongs to the Special Issue Teaching Augustine)
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